OR1D2_PANTR
ID OR1D2_PANTR Reviewed; 312 AA.
AC Q9TUA8;
DT 07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Olfactory receptor 1D2;
GN Name=OR1D2;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10512677; DOI=10.1006/geno.1999.5900;
RA Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T.,
RA Lancet D.;
RT "Primate evolution of an olfactory receptor cluster: diversification by
RT gene conversion and recent emergence of pseudogenes.";
RL Genomics 61:24-36(1999).
CC -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AF101731; AAF03316.1; -; Genomic_DNA.
DR RefSeq; NP_001009114.1; NM_001009114.1.
DR AlphaFoldDB; Q9TUA8; -.
DR SMR; Q9TUA8; -.
DR STRING; 9598.ENSPTRP00000054946; -.
DR PaxDb; Q9TUA8; -.
DR Ensembl; ENSPTRT00000062389; ENSPTRP00000054946; ENSPTRG00000051800.
DR GeneID; 468145; -.
DR KEGG; ptr:468145; -.
DR CTD; 4991; -.
DR VGNC; VGNC:9492; OR1D2.
DR eggNOG; ENOG502T9JB; Eukaryota.
DR GeneTree; ENSGT00940000160386; -.
DR InParanoid; Q9TUA8; -.
DR OMA; PFGFMII; -.
DR OrthoDB; 971471at2759; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000051800; Expressed in testis.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..312
FT /note="Olfactory receptor 1D2"
FT /id="PRO_0000150420"
FT TOPO_DOM 1..25
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..49
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 50..57
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..79
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 80..100
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..120
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 121..139
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..158
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 159..196
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..219
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 220..236
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..259
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 260..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..291
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 292..312
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 5
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 195
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 97..189
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 312 AA; 35212 MW; 460E872B721CEFA3 CRC64;
MDGGNQSEGS EFLLLGMSES PEQQRILFWM FLSMYLVTVV GNVLIILAIS SDSCLHTPMY
FFLANLSFTD LFFVTNTIPK MLVNLQSQNK AISYAGCLTQ LYFLVSLVAL DNLILAVMAY
DRYVAICCPL HYTTAMSPKL CILLLSLCWV LSVLYGLIHT LLMTRVTFCG SRKIHYIFCE
MYVLLRMACS NIQTNHTVLI ATGCFIFLIP FGFVIISYVL IIRAILRIPS LSKKYKAFST
CASHLGAVSL FYGTLCMVYL KPLHTYSVKD SVATVMYAVV TPMMNPFIYS LRNKDMHGAL
GRLLDKHFKR LT
