OR1D2_PONPY
ID OR1D2_PONPY Reviewed; 313 AA.
AC Q9TU84;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 26-FEB-2020, entry version 78.
DE RecName: Full=Olfactory receptor 1D2;
GN Name=OR1D2;
OS Pongo pygmaeus (Bornean orangutan).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9600;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10512677; DOI=10.1006/geno.1999.5900;
RA Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T.,
RA Lancet D.;
RT "Primate evolution of an olfactory receptor cluster: diversification by
RT gene conversion and recent emergence of pseudogenes.";
RL Genomics 61:24-36(1999).
CC -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AF101767; AAF03342.1; -; Genomic_DNA.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Sensory transduction; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..313
FT /note="Olfactory receptor 1D2"
FT /id="PRO_0000285557"
FT TOPO_DOM 1..25
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..49
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 50..57
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..79
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 80..100
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..120
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 121..139
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..158
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 159..196
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..219
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 220..236
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..259
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 260..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..291
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 292..313
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 5
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 195
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 97..189
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 313 AA; 35269 MW; B512163381EBF18C CRC64;
MDGGNQSEGS EFLLLGMSES PEQQRILFWM FLSMYLVTVL GNVLIILAIS SDSRLHTPMY
FFLANLSFTD LFFVTNTIPK MLVNLQSQDK AISYAGCLTQ LYFLLSLVTL DNLILAVMAY
DRYVAICCPL HYVTAMSPRL CILLLSLCWV FSVLYGLIHT LLMTRVTFCG SRKIHYLFCE
MYFLLRLACS NIQINHTVLX ATGCFIFLIP LGFMIXSYAR IVRAILRIPS ATGKYKAFST
CASHLAVVSL FYGTLGMVYL QPLQTYSTKD SVATVMYAVV TPMMNPFIYS LRNKDIHGAL
GRLLQGKAFQ KLT
