ID   OR1E2_PANTR             Reviewed;         314 AA.
AC   Q9TUA2;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Olfactory receptor 1E2;
DE   AltName: Full=Olfactory receptor 1E4;
GN   Name=OR1E2; Synonyms=OR1E4;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10512677; DOI=10.1006/geno.1999.5900;
RA   Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T.,
RA   Lancet D.;
RT   "Primate evolution of an olfactory receptor cluster: diversification by
RT   gene conversion and recent emergence of pseudogenes.";
RL   Genomics 61:24-36(1999).
CC   -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; AF101740; AAF03322.1; -; Genomic_DNA.
DR   RefSeq; NP_001009162.1; NM_001009162.1.
DR   AlphaFoldDB; Q9TUA2; -.
DR   SMR; Q9TUA2; -.
DR   STRING; 9598.ENSPTRP00000014616; -.
DR   PaxDb; Q9TUA2; -.
DR   GeneID; 494121; -.
DR   KEGG; ptr:494121; -.
DR   CTD; 8388; -.
DR   eggNOG; ENOG502SI5J; Eukaryota.
DR   InParanoid; Q9TUA2; -.
DR   OrthoDB; 924696at2759; -.
DR   Proteomes; UP000002277; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..314
FT                   /note="Olfactory receptor 1E2"
FT                   /id="PRO_0000150429"
FT   TOPO_DOM        1..25
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..49
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        50..57
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..79
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..100
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..120
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        121..139
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..158
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        159..196
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..219
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..236
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..260
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        261..272
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..292
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        293..314
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        5
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        265
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        97..189
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   314 AA;  35243 MW;  540D6BA610674E0F CRC64;
     MMGQNQTSIS DFLLLGLPIQ PEQQNLCYAL FLAMYLTTLL GNLLIIVLIR LDSHLHTPMY
     LFLSNLSFSD LCFSSVTIPK LLQNMQNQDP SIPYADCLTQ MHFFLLFGDL ESFLLVAMAY
     DRYVAICFPL HYTAIMSPML CLSVVALSWV LTTFHAMLHT LLMARLCFCA DNVIPHFFCD
     MSALLKLACS DTRVNEWVIF IMGGLIVVIP FLLILGSYAR IVSSILKVPS FKGICKALST
     CGSHLSVVSL FYGTVIGLYL CPSANSSTLK DTVMAMMYTV VTPMLNPFIY SLRNRDMKGA
     LERVICKRKN PFLL