ID   ASA1_PENRW              Reviewed;         440 AA.
AC   B6HHJ8;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=asa1; ORFNames=Pc21g05520;
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255;
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; AM920436; CAP95449.1; -; Genomic_DNA.
DR   RefSeq; XP_002567598.1; XM_002567552.1.
DR   AlphaFoldDB; B6HHJ8; -.
DR   STRING; 1108849.XP_002567598.1; -.
DR   EnsemblFungi; CAP95449; CAP95449; PCH_Pc21g05520.
DR   GeneID; 8313849; -.
DR   KEGG; pcs:Pc21g05520; -.
DR   VEuPathDB; FungiDB:PCH_Pc21g05520; -.
DR   eggNOG; KOG0322; Eukaryota.
DR   HOGENOM; CLU_041940_0_1_1; -.
DR   OMA; NSLCFQE; -.
DR   OrthoDB; 1543596at2759; -.
DR   BioCyc; PCHR:PC21G05520-MON; -.
DR   Proteomes; UP000000724; Contig Pc00c21.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..440
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402216"
FT   REPEAT          20..59
FT                   /note="WD 1"
FT   REPEAT          62..104
FT                   /note="WD 2"
FT   REPEAT          196..238
FT                   /note="WD 3"
FT   REPEAT          259..300
FT                   /note="WD 4"
FT   REPEAT          315..354
FT                   /note="WD 5"
FT   REPEAT          357..399
FT                   /note="WD 6"
FT   REPEAT          403..440
FT                   /note="WD 7"
FT   REGION          376..399
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   440 AA;  48139 MW;  518EB1FAE49D8425 CRC64;
     MDTKSVQVQS PATPVYILRG HASPVHALHI YSQNLRLVSG DANGWIVVWD LVTKRPVTAW
     KAHEGAVLEA RGFDVGSGAT EIYTHGRDHK LCVWKLRPED ETFLNKTLPV DATESAQPGS
     KTQPWLLHSL PVNALNFCAF SMAFVNPDGL PAFPSQSGRP ENTLFAVPNA LDSGGVDIFH
     LPSERRISTI PSEQSPKTGM LMAVNLFISP SGDLYVASAY EDGHVMVFVH RGALKSASFE
     REYISNNPLK WDKLYAGRPH SQPVLSLDVA PSHGYFISSS ADALIVKHPI PNTGSAGYIP
     TAGYKEESPL KIVNTKHSGQ QGLRIRSDEK VFATAGWDSR IRVYSGKTMK ELAVLKWHKD
     GCYSIAFGDT ESMSSLVSPS SESAKQEPRD ADQGAAGQTT VDGRNYSLAT VQQQRNQKVQ
     QTHWLAAGSK DGKISLWDIY