ID   ASA1_PICST              Reviewed;         432 AA.
AC   A3LXM4;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; Synonyms=CAF4; ORFNames=PICST_32865;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; CP000500; ABN67826.2; -; Genomic_DNA.
DR   RefSeq; XP_001385855.2; XM_001385818.1.
DR   AlphaFoldDB; A3LXM4; -.
DR   STRING; 4924.XP_001385855.2; -.
DR   EnsemblFungi; ABN67826; ABN67826; PICST_32865.
DR   GeneID; 4840372; -.
DR   KEGG; pic:PICST_32865; -.
DR   eggNOG; KOG0322; Eukaryota.
DR   HOGENOM; CLU_045414_0_0_1; -.
DR   InParanoid; A3LXM4; -.
DR   OMA; LVCCNTQ; -.
DR   OrthoDB; 1543596at2759; -.
DR   Proteomes; UP000002258; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..432
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402219"
FT   REPEAT          14..55
FT                   /note="WD 1"
FT   REPEAT          58..96
FT                   /note="WD 2"
FT   REPEAT          100..144
FT                   /note="WD 3"
FT   REPEAT          258..296
FT                   /note="WD 4"
FT   REPEAT          395..432
FT                   /note="WD 5"
SQ   SEQUENCE   432 AA;  48724 MW;  DEF7286B6AB2D878 CRC64;
     MDNTTPQQIF SLRSHENSIS NIEEVFLWNK HCLISSDTKG WIIIWNINAK RPIRKWQAHD
     ETILTLTLIS TNTLLTHGRD ASLKIWDISV EHAESSPPEL FFLPINTLNF CNVQYFNDFL
     ITPASVDSNN FDIYKITNPE YEFKRVLANF SPFDLYSKNK TEINSPNEQG RNDFGIIMKL
     VYVEHSNQLF LGFESGQIIG LNINLNPDAT LVDKTTEAYS KKTPSKYGGL SSLIDKTSSR
     TLINKEPRVN LIYSDSSHIP NPITSLVHLK DNILISGSTN KQVIVHHYQM HSIDSSDAHL
     DVKKVAHSGI QSIVADEKTD TIFIGHWNGV IEGVDYKSNK KKLDSQFELK RDLPHLITTS
     TNSSGGDTNT IAKEAVKLTS LALSIERENT QVTTTKKKSY KDLVKARSAY IGNDNRLLFA
     GYEDGAVVAY RL