ID   ASA1_SCHJY              Reviewed;         365 AA.
AC   B6K7R8;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=asa1; ORFNames=SJAG_04784;
OS   Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=402676;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=yFS275 / FY16936;
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KE651168; EEB09572.1; -; Genomic_DNA.
DR   RefSeq; XP_002175865.1; XM_002175829.2.
DR   AlphaFoldDB; B6K7R8; -.
DR   SMR; B6K7R8; -.
DR   STRING; 4897.EEB09572; -.
DR   EnsemblFungi; EEB09572; EEB09572; SJAG_04784.
DR   GeneID; 7049370; -.
DR   VEuPathDB; FungiDB:SJAG_04784; -.
DR   eggNOG; KOG0322; Eukaryota.
DR   HOGENOM; CLU_041940_0_1_1; -.
DR   OMA; AWDLTIM; -.
DR   OrthoDB; 1543596at2759; -.
DR   Proteomes; UP000001744; Unassembled WGS sequence.
DR   GO; GO:0070209; C:ASTRA complex; IEA:EnsemblFungi.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..365
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402220"
FT   REPEAT          12..50
FT                   /note="WD 1"
FT   REPEAT          53..91
FT                   /note="WD 2"
FT   REPEAT          188..230
FT                   /note="WD 3"
FT   REPEAT          245..284
FT                   /note="WD 4"
FT   REPEAT          292..330
FT                   /note="WD 5"
FT   REPEAT          333..365
FT                   /note="WD 6"
SQ   SEQUENCE   365 AA;  40368 MW;  66F4648520952807 CRC64;
     MVVPTPFFVL RGHLSSVTSL SFVSDGILYS GDANGWMICW DLSVMRPTHI WRAHTKSILG
     VYGCSSEVVW THGRDMQVAR WHLNPPTGGS HIPLSLLHAI QQEKKNDQQS SSSLTIVSSV
     HKGYFFQTNN LTFCSFAISP AAGLLVVPNT VNAEQLDVYA LNDTSDSDRR DNCGKRLQHA
     LEPKPQIEKT GAVMSVALHV KYNKVVLVAG YESGHVVQYI ADVDAAQKVN VYFQQVWQVM
     YAEKVHKEPV LSVVFGNDNG YLYSSSADDY IVRHTICLSK ETHTNPESMK TGHPGQQCLR
     VRSDDKILVS AGWDGRGRVY GAKSLAKLAV LKYHSETCNC AAIQPGSNLI ALGSKDSRIS
     LWQIY