OR3A2_GORGO
ID OR3A2_GORGO Reviewed; 315 AA.
AC Q9TU88;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Olfactory receptor 3A2;
GN Name=OR3A2;
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10512677; DOI=10.1006/geno.1999.5900;
RA Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T.,
RA Lancet D.;
RT "Primate evolution of an olfactory receptor cluster: diversification by
RT gene conversion and recent emergence of pseudogenes.";
RL Genomics 61:24-36(1999).
CC -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AF101762; AAF03338.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9TU88; -.
DR SMR; Q9TU88; -.
DR STRING; 9593.ENSGGOP00000010256; -.
DR eggNOG; ENOG502RU1B; Eukaryota.
DR HOGENOM; CLU_012526_8_1_1; -.
DR InParanoid; Q9TU88; -.
DR Proteomes; UP000001519; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..315
FT /note="Olfactory receptor 3A2"
FT /id="PRO_0000246147"
FT TOPO_DOM 1..29
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..52
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 53..60
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..82
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 83..103
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..123
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..143
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..161
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 162..199
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 200..223
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 224..240
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 241..264
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 265..275
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..295
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 296..315
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 8
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 100..192
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 315 AA; 34374 MW; 8E11BF3771437608 CRC64;
MEPEAGTNRT AVAEFILLGL VQTEEMQSVV FVLLLFAYLV TIGGNLSILA AVLVEPKLHA
PMYFFLGNLS VLDVGCITVT VPAMLGRLLS HKSTISYDAC LSQLFFFHLL AGMDCFLLTA
MAYDRFLAIC QPLTYSTRMN QRVQRMLVAA SWTCAFTNAL THTIALTTLN FCGPNEVNHF
YCDLPQLFQL SCSSTQLSEL LLFVAAAFMA VAPLVFISVS YAHVVAAVLQ IHSAEGRKKA
FSTCGSHLTV VGIFYGTGVF SYMRLGSVES SDKDKGVGVF MTVINPMLNP LIYSLRNTDV
QGALCQLLVG KRSLT