OR3A2_PANTR
ID OR3A2_PANTR Reviewed; 315 AA.
AC Q9TU97;
DT 07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Olfactory receptor 3A2;
GN Name=OR3A2;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10512677; DOI=10.1006/geno.1999.5900;
RA Sharon D., Glusman G., Pilpel Y., Khen M., Gruetzner F., Haaf T.,
RA Lancet D.;
RT "Primate evolution of an olfactory receptor cluster: diversification by
RT gene conversion and recent emergence of pseudogenes.";
RL Genomics 61:24-36(1999).
CC -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AF101746; AAF03327.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9TU97; -.
DR SMR; Q9TU97; -.
DR STRING; 9598.ENSPTRP00000054937; -.
DR PaxDb; Q9TU97; -.
DR eggNOG; ENOG502RU1B; Eukaryota.
DR InParanoid; Q9TU97; -.
DR Proteomes; UP000002277; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..315
FT /note="Olfactory receptor 3A2"
FT /id="PRO_0000150519"
FT TOPO_DOM 1..29
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..52
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 53..60
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..82
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 83..103
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..123
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..143
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..161
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 162..199
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 200..223
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 224..240
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 241..264
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 265..275
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..295
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 296..315
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 8
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 100..192
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 315 AA; 34750 MW; 61CE72577F296C6D CRC64;
MEPEAGTNRT AVAEFILLGL VQTEEMQPVV FVLFLFAYLV TIGGNLSILA AILVEPKLHA
PMYFFLGNLS VLDVGCITVT VPAMLGRLLS HKSTISYDAC LSQLFFFHLL AGMDCFLLTA
MAYDRFLAIC WPLTYSTRMS QTVQRMLVAA SWACAFTNAL THTVAMSTLN FCGPNEVNHF
YCDLPQLFQL SCSSTQLNEL LLFAVGFIMA GTPLVLIITS YSHVAAAVLR IRSVEGWKKA
FSTCGSHLTV VCLFFGTGIF NYMRLGSEEA SDKDKGVGVF NTVINPMLNP LIYSLRNPDV
QGALWRIFLG RRSLT