ID   ASA1_YARLI              Reviewed;         428 AA.
AC   Q6CFV3;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; OrderedLocusNames=YALI0B03388g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; CR382128; CAG82685.1; -; Genomic_DNA.
DR   RefSeq; XP_500459.1; XM_500459.1.
DR   AlphaFoldDB; Q6CFV3; -.
DR   STRING; 4952.CAG82685; -.
DR   EnsemblFungi; CAG82685; CAG82685; YALI0_B03388g.
DR   GeneID; 2907496; -.
DR   KEGG; yli:YALI0B03388g; -.
DR   VEuPathDB; FungiDB:YALI0_B03388g; -.
DR   HOGENOM; CLU_041940_0_1_1; -.
DR   InParanoid; Q6CFV3; -.
DR   OMA; ETHEEDL; -.
DR   Proteomes; UP000001300; Chromosome B.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..428
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402224"
FT   REPEAT          15..52
FT                   /note="WD 1"
FT   REPEAT          55..93
FT                   /note="WD 2"
FT   REPEAT          122..163
FT                   /note="WD 3"
FT   REPEAT          171..209
FT                   /note="WD 4"
FT   REPEAT          217..259
FT                   /note="WD 5"
FT   REPEAT          323..362
FT                   /note="WD 6"
FT   REPEAT          364..418
FT                   /note="WD 7"
FT   REGION          250..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        250..286
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   428 AA;  47792 MW;  F9F183CF7907EB4C CRC64;
     MDLSGAPVPV ALLRGHTHPV TSLRFYNAFL VSGDESGWVF WWSLVTRRPL AIWKAHHEAI
     LSLVWMDETH LLTQGRDDKL YVWRLELDAQ GKSGLSVKPP SSLVADDPTD YPKPWLTYSL
     TVNSLNFCQV AWVNGLLAKP DLDSSDKVEL LEWTDGAFRV VWNDIYPRLN GIKTGIVMDL
     NIMNKKLIVG YEGGAVAVFD ISDRNRYTPV LNYYVVSHVQ PVLSVRAHPT KKEFVSSSAD
     SLIVKHPIKD QVVPEEEMEE PEPAKNSERP PSPKIVEVED SPELEPPKNV VRGFDVPGLE
     LEEGIEVKEE EKPESKPLDA VNVRHSGLSS LQLDSDGDLI MTAGWDGKVR LFTYDDISKV
     SVFHEREGVG CVAFSTPTTS DTANPRLAKA LTTRWIAVGG KDGKIELYTI QQGNEKTLGE
     GRSKYIRH