ID   ASA1_YEAS1              Reviewed;         443 AA.
AC   B3LK55;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; ORFNames=SCRG_02567;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex
CC       composed of at least RVB1, RVB2, TRA1, TEL2, TTI1 and TTI2.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH408046; EDV11283.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LK55; -.
DR   EnsemblFungi; EDV11283; EDV11283; SCRG_02567.
DR   HOGENOM; CLU_045414_1_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Repeat; WD repeat.
FT   CHAIN           1..443
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402225"
FT   REPEAT          23..67
FT                   /note="WD 1"
FT   REPEAT          71..110
FT                   /note="WD 2"
FT   REPEAT          258..295
FT                   /note="WD 3"
FT   REPEAT          318..359
FT                   /note="WD 4"
FT   REGION          372..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   443 AA;  50563 MW;  2EF7AC0A161DED82 CRC64;
     MRGFSNEIIL KRTLTLSDFT LRYHKRGITA LQVIKAPSVS NVPVLLSGDN YGYFVMWDLV
     TKRPITHIEI EGNSHIIAFW WVETTNVLYI LSKDSMLRIF ELDSSTQLSI DLVRKLSQAN
     KTDHLQWTKI YEMPINTLNF ANFIIEAEVK PTKDNKSYRL VCCHTDDSET IDIYQIIEDS
     TFKLKRPFNN INFPRFLKQQ NFLGISKDSK FGIIMRFAKL NDVIFLGYEN GFVVGFKITF
     DEGLQRDIAE LVHVSNDHYP NPILDMCVSG DELYSCSTDD FITKYKIPVN LQLETKYLRD
     DALLIKCPSS LRVSEPSKVH LPLKNIGHID KVKDDYLVVS SWSGMTIVYN MRTSEVEQTF
     VKSKNNLVVS DSSMGDLTNG SGSNTESSSK SHNYKVGAMT CLESFDVQSD GLRLGQLRRI
     KALAKCNWCL IGYEDGTIKL NKI