ID   ASA1_YEAS2              Reviewed;         443 AA.
AC   C7GPS8;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; ORFNames=C1Q_02314;
OS   Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=574961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAY291;
RX   PubMed=19812109; DOI=10.1101/gr.091777.109;
RA   Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA   Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA   Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA   Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA   Pereira G.A.G.;
RT   "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT   bioethanol production.";
RL   Genome Res. 19:2258-2270(2009).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex
CC       composed of at least RVB1, RVB2, TRA1, TEL2, TTI1 and TTI2.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; ACFL01000094; EEU07195.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7GPS8; -.
DR   Proteomes; UP000008073; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Repeat; WD repeat.
FT   CHAIN           1..443
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402226"
FT   REPEAT          23..67
FT                   /note="WD 1"
FT   REPEAT          71..110
FT                   /note="WD 2"
FT   REPEAT          258..295
FT                   /note="WD 3"
FT   REPEAT          318..359
FT                   /note="WD 4"
FT   REGION          372..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   443 AA;  50624 MW;  9BEFE88279B74FDA CRC64;
     MRGFSNEIIL KRTLTLSDFT LRYHKRGITA LQVIKAPSVS NVPVLLSGDN YGYFVMWDLV
     TKRPITHMEI EGNSHIIAFW WVETTNVLYI LSKDSMLRIF ELDSSTQRSI DLVRKLSQAN
     KTDHLQWTKI YEMPINTLNF ANFIIEAEVK PTKDNKSYRL VCCHTDDSET IDIYQIIEDS
     TFKLKRPFNN INFPRFLKQQ NFLGISKDSK FGIIMRFAKL NDVIFLGYEN GFVVGFKITF
     DEGLQRDIAE LVHVSNDHYP NPILDMCVSG DELYSCSTDD FITKYKIPVN LQLETKYLRD
     DALLIKCPSS LRVSEPSKVH LPLKNIGHID KVKDDYLVVS SWSGMTIVYN MRTSEVEQTF
     VKSKNNLVVS DSSMGDLTNG SGSNTESSSK SHNYKVGAMT CLESFDVQSD GLRLGQLRRI
     KALAKCNWCL IGYEDGTIKL NKI