ID   ASA1_ZYGRC              Reviewed;         397 AA.
AC   C5DUI6;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; OrderedLocusNames=ZYRO0C17050g;
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; CU928175; CAR27447.1; -; Genomic_DNA.
DR   RefSeq; XP_002496380.1; XM_002496335.1.
DR   AlphaFoldDB; C5DUI6; -.
DR   STRING; 559307.C5DUI6; -.
DR   EnsemblFungi; CAR27447; CAR27447; ZYRO0C17050g.
DR   GeneID; 8203611; -.
DR   KEGG; zro:ZYRO0C17050g; -.
DR   HOGENOM; CLU_045414_1_0_1; -.
DR   InParanoid; C5DUI6; -.
DR   Proteomes; UP000008536; Chromosome C.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..397
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402229"
FT   REPEAT          16..56
FT                   /note="WD 1"
FT   REPEAT          212..252
FT                   /note="WD 2"
FT   REGION          324..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   397 AA;  45072 MW;  2338777E82DFC408 CRC64;
     MNPIQLPEYT LRFHKSSVTD LLVLDLPQEV APLLVSGDAT GKICLWDLIR RRPISSHCIE
     NEPQIVALQY VDDGLLAVLD KQHKLRFLKI DGSWEQVYEI PVNTLNFANF LVQRLDTGWY
     RLICCNTQDS ESIDIYEFHL SSLHSLKRVH KGLKFYQAIS SLILPAGFKL DKLGIVMKFT
     EWHGVIFCGM ESGFVIGFNL IDDGQVEIVY VSHVHYPNPI LDLYPGKDNI LSSSTDNKIG
     IHDLNCQQDE RPNFERQSPI LLKKELHSLS ANFKQVPISE VAHIKKIENL LLLSSWFGET
     VVTDEQIELL AKFSKSKSIV EVNENPQGNL QSNNTSSKSK NPNCKVSSLE GLSSSNSKDS
     NYVISTNVGQ RRRIERFLQN SWCIIGYDDG NIAFHRL