ID   OR6J1_HUMAN             Reviewed;         347 AA.
AC   Q8NGC5;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Olfactory receptor 6J1;
DE   AltName: Full=Olfactory receptor 6J2;
GN   Name=OR6J1; Synonyms=OR6J2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,
RA   Tsutsumi S., Aburatani H., Asai K., Akiyama Y.;
RT   "Genome-wide discovery and analysis of human seven transmembrane helix
RT   receptor genes.";
RL   Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC   -!- WEB RESOURCE: Name=Human Olfactory Receptor Data Exploratorium (HORDE);
CC       URL="http://genome.weizmann.ac.il/horde/card/index/symbol:OR6J2";
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DR   EMBL; AB065892; BAC06108.1; -; Genomic_DNA.
DR   CCDS; CCDS86371.1; -.
DR   AlphaFoldDB; Q8NGC5; -.
DR   SMR; Q8NGC5; -.
DR   IntAct; Q8NGC5; 1.
DR   STRING; 9606.ENSP00000437629; -.
DR   GlyGen; Q8NGC5; 1 site.
DR   BioMuta; OR6J1; -.
DR   DMDM; 38372666; -.
DR   MassIVE; Q8NGC5; -.
DR   PaxDb; Q8NGC5; -.
DR   PeptideAtlas; Q8NGC5; -.
DR   PRIDE; Q8NGC5; -.
DR   Antibodypedia; 73085; 18 antibodies from 10 providers.
DR   Ensembl; ENST00000540461.2; ENSP00000437629.1; ENSG00000255804.2.
DR   UCSC; uc058zia.1; human.
DR   GeneCards; OR6J1; -.
DR   HGNC; HGNC:14707; OR6J1.
DR   HPA; ENSG00000255804; Tissue enhanced (brain).
DR   neXtProt; NX_Q8NGC5; -.
DR   VEuPathDB; HostDB:ENSG00000255804; -.
DR   eggNOG; ENOG502SI3J; Eukaryota.
DR   HOGENOM; CLU_012526_1_1_1; -.
DR   InParanoid; Q8NGC5; -.
DR   PhylomeDB; Q8NGC5; -.
DR   TreeFam; TF336833; -.
DR   PathwayCommons; Q8NGC5; -.
DR   Reactome; R-HSA-9752946; Expression and translocation of olfactory receptors.
DR   SignaLink; Q8NGC5; -.
DR   ChiTaRS; OR6J1; human.
DR   Pharos; Q8NGC5; Tdark.
DR   PRO; PR:Q8NGC5; -.
DR   Proteomes; UP000005640; Chromosome 14.
DR   RNAct; Q8NGC5; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..347
FT                   /note="Olfactory receptor 6J1"
FT                   /id="PRO_0000150628"
FT   TOPO_DOM        1..24
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        25..45
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        46..53
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        75..98
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        120..138
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        160..196
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..216
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        217..236
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..257
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        258..270
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        292..347
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        96..188
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   347 AA;  38693 MW;  69A4D98D2075920C CRC64;
     MGNWTAAVTE FVLLGFSLSR EVELLLLVLL LPTFLLTLLG NLLIISTVLS CSRLHTPMYF
     FLCNLSILDI LFTSVISPKV LANLGSRDKT ISFAGCITQC YFYFFLGTVE FLLLTVMSYD
     RYATICCPLR YTTIMRPSVC IGTVVFSWVG GFLSVLFPTI LISQLPFCGS NIINHFFCDS
     GPLLALACAD TTAIELMDFM LSSMVILCCI VLVAYSYTYI ILTIVRIPSA SGRKKAFNTC
     ASHLTIVIIP SGITVFIYVT PSQKEYLEIN KIPLVLSSVV TPFLNPFIYT LRNDTVQGVL
     RDVWVRVRGV FEKRMRAVLR SRLSSNKDHQ GRACSSPPCV YSVKLQC