ID   ORC2_ORYSI              Reviewed;         379 AA.
AC   B8APQ0;
DT   07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Origin of replication complex subunit 2 {ECO:0000305};
DE            Short=OsORC2 {ECO:0000305};
GN   ORFNames=OsI_10291 {ECO:0000312|EMBL:EEC74646.1};
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946 {ECO:0000312|EMBL:EEC74646.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Essential protein (By similarity). Component of the origin
CC       recognition complex (ORC) that binds origins of replication. DNA-
CC       binding is ATP-dependent, however specific DNA sequences that define
CC       origins of replication have not been identified so far. ORC is required
CC       to assemble the pre-replication complex necessary to initiate DNA
CC       replication (By similarity). {ECO:0000250,
CC       ECO:0000250|UniProtKB:Q38899}.
CC   -!- SUBUNIT: Component of the origin recognition complex (ORC) composed of
CC       at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a
CC       cell-cycle and development dependent manner. It is sequentially
CC       assembled at the exit from anaphase of mitosis and disassembled as
CC       cells enter S phase. {ECO:0000250|UniProtKB:Q38899}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ORC2 family. {ECO:0000305}.
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DR   EMBL; CM000128; EEC74646.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8APQ0; -.
DR   SMR; B8APQ0; -.
DR   STRING; 39946.B8APQ0; -.
DR   EnsemblPlants; BGIOSGA011320-TA; BGIOSGA011320-PA; BGIOSGA011320.
DR   Gramene; BGIOSGA011320-TA; BGIOSGA011320-PA; BGIOSGA011320.
DR   HOGENOM; CLU_018596_1_0_1; -.
DR   OMA; YDFELAY; -.
DR   Proteomes; UP000007015; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR007220; ORC2.
DR   PANTHER; PTHR14052; PTHR14052; 1.
DR   Pfam; PF04084; ORC2; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..379
FT                   /note="Origin of replication complex subunit 2"
FT                   /id="PRO_0000431430"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   379 AA;  42590 MW;  64FAD98F4781A6C3 CRC64;
     MALRGGHAAA AAGVSSGSED DDEEAGFSRS YFLAKEKEPS SGKKRARAAG KLSDLNLVDE
     QVLRASLAEI PPKHEREVEA LTRSYKEQYR NWLFELRCGF GLLMYGFGSK KMLLEDFAST
     TLSDFTVIVV NGYLPSINLK QVIVTIAEIF WEQTKLKRKR QTATRSQLQP FASQSIDDII
     SFLNNQTSDN GDDNVCLLIH NIDGPALRDA ESQQYLAQVS CCPQVHVVAS VDHVNAPLLW
     DKKMVHTQFK WSWYHVPTFA PYKVEGVFYP LILASGGHAQ TMKTALVVLQ SLTPNAQSVF
     RVLAEYQLAH EKEEGMHFSS LYTKCRERFL VSSQVTLNSH LTEFKDHDLV KIRKHSDGQD
     CLHIPLVSDA LEKLLQELT