ORC2_ORYSJ
ID ORC2_ORYSJ Reviewed; 379 AA.
AC Q10QS7; A0A0N7KGQ4; Q852P2; Q9XFD6;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Origin of replication complex subunit 2 {ECO:0000303|PubMed:15939553};
DE Short=OsORC2 {ECO:0000303|PubMed:15939553};
GN Name=ORC2 {ECO:0000303|PubMed:15939553};
GN OrderedLocusNames=LOC_Os03g08640 {ECO:0000305}, Os03g0184700 {ECO:0000305};
GN ORFNames=OsJ_09689 {ECO:0000312|EMBL:EEE58456.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000312|Proteomes:UP000059680};
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Zhenxian 97B; TISSUE=Panicle;
RX PubMed=16215849; DOI=10.1007/s10529-005-0937-4;
RA Li K.-G., Yang J.-S., Attia K., Su W., He G.-M., Qian X.-Y.;
RT "Cloning and characterization of OsORC2, a new member of rice origin
RT recognition complex.";
RL Biotechnol. Lett. 27:1355-1359(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY, GENE
RP FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=15939553; DOI=10.1016/j.gene.2005.03.047;
RA Mori Y., Yamamoto T., Sakaguchi N., Ishibashi T., Furukawa T., Kadota Y.,
RA Kuchitsu K., Hashimoto J., Kimura S., Sakaguchi K.;
RT "Characterization of the origin recognition complex (ORC) from a higher
RT plant, rice (Oryza sativa L.).";
RL Gene 353:23-30(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare; TISSUE=Pistil;
RA Kikuchi S., Adachi J., Aizawa K., Akimura T., Arakawa T., Carninci P.,
RA Doi K., Fujimura T., Fukuda S., Hanagaki T., Hara A., Hashizume W.,
RA Hayashida K., Hayashizaki Y., Hayatsu N., Hiramoto K., Hiraoka T., Hori F.,
RA Hotta I., Iida J., Iida Y., Ikeda R., Imamura K., Imotani K., Ishibiki J.,
RA Ishii Y., Ishikawa M., Itoh M., Kagawa I., Kanagawa S., Katoh H.,
RA Kawagashira N., Kawai J., Kawamata M., Kishikawa-Hirozane T., Kishimoto N.,
RA Kobayashi M., Kodama T., Kojima K., Kojima Y., Kondo S., Konno H.,
RA Kouda M., Koya S., Kurihara C., Kurosaki T., Kusumegi T., Li C., Lu M.,
RA Masuda H., Matsubara K., Matsuyama T., Miura J., Miyazaki A., Mizuno K.,
RA Murakami K., Murata M., Nagata T., Nakahama Y., Nakamura M., Namiki T.,
RA Narikawa R., Niikura J., Nishi K., Nomura K., Numasaki R., Ohneda E.,
RA Ohno M., Ohtsuki K., Oka M., Ooka H., Osato N., Ota Y., Otomo Y., Ryu R.,
RA Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Sato K.,
RA Satoh K., Shibata K., Shinagawa A., Shiraki T., Shishiki T., Sogabe Y.,
RA Sugano S., Sugiyama A., Suzuki K., Suzuki Y., Tagami M., Tagami-Takeda Y.,
RA Tagawa A., Takahashi F., Takaku-Akahira S., Tanaka T., Tomaru A., Toya T.,
RA Tsunoda Y., Ueda M., Waki K., Xie Q., Yahagi W., Yamada H., Yamamoto M.,
RA Yasunishi A., Yazaki J., Yokomizo S., Yoshimura A., Eguchi K., Kanamori H.,
RA Yamagata H., Kamiya K., Kurita K., Kikuta A., Bito T.;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [9]
RP REVIEW ON THE CORE DNA REPLICATION MACHINERY.
RX PubMed=17556508; DOI=10.1104/pp.107.101105;
RA Shultz R.W., Tatineni V.M., Hanley-Bowdoin L., Thompson W.F.;
RT "Genome-wide analysis of the core DNA replication machinery in the higher
RT plants Arabidopsis and rice.";
RL Plant Physiol. 144:1697-1714(2007).
CC -!- FUNCTION: Essential protein (By similarity). Component of the origin
CC recognition complex (ORC) that binds origins of replication. DNA-
CC binding is ATP-dependent, however specific DNA sequences that define
CC origins of replication have not been identified so far. ORC is required
CC to assemble the pre-replication complex necessary to initiate DNA
CC replication (By similarity). {ECO:0000250,
CC ECO:0000250|UniProtKB:Q38899}.
CC -!- SUBUNIT: Component of the origin recognition complex (ORC) composed of
CC at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a
CC cell-cycle and development dependent manner. It is sequentially
CC assembled at the exit from anaphase of mitosis and disassembled as
CC cells enter S phase. {ECO:0000250|UniProtKB:Q38899}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15939553}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in roots, seedling and
CC inflorescence meristem, and, to a lower extent, in mature leaves and
CC shoot. Higher levels in inflorescence meristem than in shoot apical
CC meristem (SAM). {ECO:0000269|PubMed:15939553,
CC ECO:0000269|PubMed:16215849}.
CC -!- SIMILARITY: Belongs to the ORC2 family. {ECO:0000305}.
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DR EMBL; AF140487; AAD29700.2; -; mRNA.
DR EMBL; AB104466; BAC57497.1; -; mRNA.
DR EMBL; DP000009; ABF94350.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF11106.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS82665.1; -; Genomic_DNA.
DR EMBL; CM000140; EEE58456.1; -; Genomic_DNA.
DR EMBL; AK242821; BAH01354.1; -; mRNA.
DR RefSeq; XP_015632472.1; XM_015776986.1.
DR RefSeq; XP_015632473.1; XM_015776987.1.
DR AlphaFoldDB; Q10QS7; -.
DR SMR; Q10QS7; -.
DR STRING; 4530.OS03T0184700-01; -.
DR PaxDb; Q10QS7; -.
DR PRIDE; Q10QS7; -.
DR EnsemblPlants; Os03t0184700-01; Os03t0184700-01; Os03g0184700.
DR GeneID; 4331860; -.
DR Gramene; Os03t0184700-01; Os03t0184700-01; Os03g0184700.
DR KEGG; osa:4331860; -.
DR eggNOG; KOG2928; Eukaryota.
DR HOGENOM; CLU_018596_1_0_1; -.
DR InParanoid; Q10QS7; -.
DR OMA; YDFELAY; -.
DR OrthoDB; 1404162at2759; -.
DR PlantReactome; R-OSA-9640882; Assembly of pre-replication complex.
DR PlantReactome; R-OSA-9645850; Activation of pre-replication complex.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q10QS7; OS.
DR GO; GO:0005664; C:nuclear origin of replication recognition complex; IBA:GO_Central.
DR GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR InterPro; IPR007220; ORC2.
DR PANTHER; PTHR14052; PTHR14052; 1.
DR Pfam; PF04084; ORC2; 1.
PE 2: Evidence at transcript level;
KW DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..379
FT /note="Origin of replication complex subunit 2"
FT /id="PRO_0000431429"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 146
FT /note="I -> V (in Ref. 1; AAD29700 and 2; BAC57497)"
FT /evidence="ECO:0000305"
FT CONFLICT 185
FT /note="N -> D (in Ref. 1; AAD29700 and 2; BAC57497)"
FT /evidence="ECO:0000305"
FT CONFLICT 244
FT /note="M -> L (in Ref. 1; AAD29700 and 2; BAC57497)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 379 AA; 42590 MW; 64FAD98F4781A6C3 CRC64;
MALRGGHAAA AAGVSSGSED DDEEAGFSRS YFLAKEKEPS SGKKRARAAG KLSDLNLVDE
QVLRASLAEI PPKHEREVEA LTRSYKEQYR NWLFELRCGF GLLMYGFGSK KMLLEDFAST
TLSDFTVIVV NGYLPSINLK QVIVTIAEIF WEQTKLKRKR QTATRSQLQP FASQSIDDII
SFLNNQTSDN GDDNVCLLIH NIDGPALRDA ESQQYLAQVS CCPQVHVVAS VDHVNAPLLW
DKKMVHTQFK WSWYHVPTFA PYKVEGVFYP LILASGGHAQ TMKTALVVLQ SLTPNAQSVF
RVLAEYQLAH EKEEGMHFSS LYTKCRERFL VSSQVTLNSH LTEFKDHDLV KIRKHSDGQD
CLHIPLVSDA LEKLLQELT
