ID   ORC5_ORYSI              Reviewed;         524 AA.
AC   B8AK78;
DT   07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Origin of replication complex subunit 5 {ECO:0000305};
DE            Short=OsORC5 {ECO:0000305};
GN   ORFNames=OsI_13614 {ECO:0000312|EMBL:EEC76215.1};
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946 {ECO:0000312|EMBL:EEC76215.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Component of the origin recognition complex (ORC) that binds
CC       origins of replication. DNA-binding is ATP-dependent. The specific DNA
CC       sequences that define origins of replication have not been identified
CC       yet. ORC is required to assemble the pre-replication complex necessary
CC       to initiate DNA replication. {ECO:0000250|UniProtKB:O43913}.
CC   -!- SUBUNIT: Component of the origin recognition complex (ORC) composed of
CC       at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a
CC       cell-cycle and development dependent manner. It is sequentially
CC       assembled at the exit from anaphase of mitosis and disassembled as
CC       cells enter S phase. {ECO:0000250|UniProtKB:Q6EWX0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O43913}.
CC   -!- SIMILARITY: Belongs to the ORC5 family. {ECO:0000305}.
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DR   EMBL; CM000128; EEC76215.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8AK78; -.
DR   SMR; B8AK78; -.
DR   STRING; 39946.B8AK78; -.
DR   EnsemblPlants; BGIOSGA013599-TA; BGIOSGA013599-PA; BGIOSGA013599.
DR   Gramene; BGIOSGA013599-TA; BGIOSGA013599-PA; BGIOSGA013599.
DR   HOGENOM; CLU_028223_1_0_1; -.
DR   OMA; QLRRWHG; -.
DR   Proteomes; UP000007015; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0009744; P:response to sucrose; IEA:EnsemblPlants.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR020796; ORC5.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12705; PTHR12705; 1.
DR   Pfam; PF14630; ORC5_C; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..524
FT                   /note="Origin of replication complex subunit 5"
FT                   /id="PRO_0000431437"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..36
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         90..97
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   524 AA;  57388 MW;  6CE37D71C4326B4C CRC64;
     MSQPVTPRRT TRSSASASPS PAPASPTSPP KSRPKPSPRR QLLAAAAAPP KEDGSSADAL
     LAELPGRRAQ AMDILRLLAP APALPLMLHG GAATGKTRAL LLALRYLRPS QRLVYAALRS
     LPSPRALFAS LLSQLSATPF STSSRHRVPD KPSDFVAALR DALNGIVSQG EVVYLVFDNL
     EVVRSWDKGG QLLPLLLRLH DLLQLPQVVL VYVSSATPDA YYSMTGSVEP NYVYFPDYTV
     DEVRDILMHD HPNPKLYSSF LSVALKPLFR VTRRVDELSA VLEPLFRRYC EPLGDLKAVP
     DEGMKRRLFE HVQSHLAVAL NETFNVPMRA SMDEIKDGGS AGKGSAKRQF AGKDGLSSEL
     EFHMSVSAKY LLLSAFLASR NPATLDAALF DSTGGLDNRK RKRKSSQASM HMKDTIVEEM
     LMKGPGTFPL ERLLAIFQCI TSVSEDILDE IDCPGNMASE SGTTGLMSDV LLQLSTLCNS
     NFLSKSRSCP LEGSARYRSN IDEDLALKVA RSVNFPLSKY MYRR