ID   ORC6_ORYSI              Reviewed;         296 AA.
AC   A2YNY4;
DT   07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Origin of replication complex subunit 6 {ECO:0000305};
DE            Short=OsORC6 {ECO:0000305};
GN   ORFNames=OsI_26966 {ECO:0000312|EMBL:EAZ04795.1};
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946 {ECO:0000312|EMBL:EAZ04795.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Component of the origin recognition complex (ORC) that binds
CC       origins of replication. DNA-binding is ATP-dependent. The specific DNA
CC       sequences that define origins of replication have not been identified
CC       yet. ORC is required to assemble the pre-replication complex necessary
CC       to initiate DNA replication. {ECO:0000250|UniProtKB:Q9Y5N6}.
CC   -!- SUBUNIT: Component of the origin recognition complex (ORC) composed of
CC       at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a
CC       cell-cycle and development dependent manner. It is sequentially
CC       assembled at the exit from anaphase of mitosis and disassembled as
CC       cells enter S phase. {ECO:0000250|UniProtKB:Q9ZVH3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y5N6}.
CC   -!- SIMILARITY: Belongs to the ORC6 family. {ECO:0000305}.
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DR   EMBL; CM000132; EAZ04795.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2YNY4; -.
DR   SMR; A2YNY4; -.
DR   STRING; 39946.A2YNY4; -.
DR   EnsemblPlants; BGIOSGA023868-TA; BGIOSGA023868-PA; BGIOSGA023868.
DR   Gramene; BGIOSGA023868-TA; BGIOSGA023868-PA; BGIOSGA023868.
DR   HOGENOM; CLU_080569_0_0_1; -.
DR   OMA; RMFEKLL; -.
DR   Proteomes; UP000007015; Chromosome 7.
DR   GO; GO:0005664; C:nuclear origin of replication recognition complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0009555; P:pollen development; IEA:EnsemblPlants.
DR   InterPro; IPR008721; ORC6.
DR   InterPro; IPR020529; ORC6_met/pln.
DR   PANTHER; PTHR13394; PTHR13394; 1.
DR   Pfam; PF05460; ORC6; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..296
FT                   /note="Origin of replication complex subunit 6"
FT                   /id="PRO_0000431439"
FT   REGION          212..296
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..252
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   296 AA;  32609 MW;  A5C05328C433545B CRC64;
     MDMSSIASRL GLSGSRPVVG KAAELRRLCD VTFDSSVLGI GEVCKAIICL EIAASKFQVI
     FDRAEAVRMS GMSEKAYIRS FNALQNGLGV KTTLDVRELG IQFGCVRLIP FVQKGLSLYK
     ERFLAALPPS RRASTDFGRP VFTAASFYLC AKRHKLKVDK LKLIDLCGTS SSEFTTVSTS
     MADLCFDVFG IAKEKKDAKS IKGSRELLDV LPSKRKHDDD SDSSGESSGD DQDELDLPTY
     KRHKKMEKEA YNDWKSSVLS SNKQTKPDPA KPRKQAQLNF KKKPSDMALE VSSAAN