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ORC6_ORYSJ
ID   ORC6_ORYSJ              Reviewed;         295 AA.
AC   Q8GSL4; A0A0P0X8V6;
DT   07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Origin of replication complex subunit 6 {ECO:0000305};
DE            Short=OsORC6 {ECO:0000305};
GN   Name=ORC6 {ECO:0000305};
GN   OrderedLocusNames=LOC_Os07g43540 {ECO:0000305}, Os07g0628600 {ECO:0000305};
GN   ORFNames=OsJ_25222 {ECO:0000312|EMBL:EAZ40750.1},
GN   P0011H09.106 {ECO:0000312|EMBL:BAC20670.1},
GN   P0506F02.120 {ECO:0000312|EMBL:BAC22351.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947 {ECO:0000312|Proteomes:UP000059680};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   REVIEW ON THE CORE DNA REPLICATION MACHINERY.
RX   PubMed=17556508; DOI=10.1104/pp.107.101105;
RA   Shultz R.W., Tatineni V.M., Hanley-Bowdoin L., Thompson W.F.;
RT   "Genome-wide analysis of the core DNA replication machinery in the higher
RT   plants Arabidopsis and rice.";
RL   Plant Physiol. 144:1697-1714(2007).
CC   -!- FUNCTION: Component of the origin recognition complex (ORC) that binds
CC       origins of replication. DNA-binding is ATP-dependent. The specific DNA
CC       sequences that define origins of replication have not been identified
CC       yet. ORC is required to assemble the pre-replication complex necessary
CC       to initiate DNA replication. {ECO:0000250|UniProtKB:Q9Y5N6}.
CC   -!- SUBUNIT: Component of the origin recognition complex (ORC) composed of
CC       at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a
CC       cell-cycle and development dependent manner. It is sequentially
CC       assembled at the exit from anaphase of mitosis and disassembled as
CC       cells enter S phase. {ECO:0000250|UniProtKB:Q9ZVH3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y5N6}.
CC   -!- SIMILARITY: Belongs to the ORC6 family. {ECO:0000305}.
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DR   EMBL; AP004260; BAC20670.1; -; Genomic_DNA.
DR   EMBL; AP004306; BAC22351.1; -; Genomic_DNA.
DR   EMBL; AP008213; BAF22265.1; -; Genomic_DNA.
DR   EMBL; AP014963; BAT02758.1; -; Genomic_DNA.
DR   EMBL; CM000144; EAZ40750.1; -; Genomic_DNA.
DR   RefSeq; XP_015645695.1; XM_015790209.1.
DR   AlphaFoldDB; Q8GSL4; -.
DR   SMR; Q8GSL4; -.
DR   STRING; 4530.OS07T0628600-00; -.
DR   PaxDb; Q8GSL4; -.
DR   PRIDE; Q8GSL4; -.
DR   EnsemblPlants; Os07t0628600-00; Os07t0628600-00; Os07g0628600.
DR   GeneID; 4343985; -.
DR   Gramene; Os07t0628600-00; Os07t0628600-00; Os07g0628600.
DR   KEGG; osa:4343985; -.
DR   eggNOG; KOG4557; Eukaryota.
DR   HOGENOM; CLU_080569_0_0_1; -.
DR   InParanoid; Q8GSL4; -.
DR   OMA; RMFEKLL; -.
DR   OrthoDB; 1522235at2759; -.
DR   PlantReactome; R-OSA-9640882; Assembly of pre-replication complex.
DR   PlantReactome; R-OSA-9645850; Activation of pre-replication complex.
DR   Proteomes; UP000000763; Chromosome 7.
DR   Proteomes; UP000007752; Chromosome 7.
DR   Proteomes; UP000059680; Chromosome 7.
DR   Genevisible; Q8GSL4; OS.
DR   GO; GO:0005664; C:nuclear origin of replication recognition complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR   GO; GO:0009555; P:pollen development; IEA:EnsemblPlants.
DR   InterPro; IPR008721; ORC6.
DR   InterPro; IPR020529; ORC6_met/pln.
DR   PANTHER; PTHR13394; PTHR13394; 1.
DR   Pfam; PF05460; ORC6; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..295
FT                   /note="Origin of replication complex subunit 6"
FT                   /id="PRO_0000431438"
FT   REGION          212..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..252
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   295 AA;  32606 MW;  01712BCEC186E4EF CRC64;
     MDMSSIASRL GLSGSRPVVR KAAELRRLCD VTFDSSVLGI GEVCKAIICL EIAASKFQVI
     FDRAEAVRMS GMSEKAYIRS FNALQNGLGV KTTLDVRELG IQFGCVRLIP FVQKGLSLYK
     ERFLAALPPS RRASTDFGRP VFTAAAFYLC AKRHKLKVDK LKLIDLCGTS SSEFTTVSTS
     MADLCFDVFG IAKEKKDAKS IKGSRELLDV LPSKRKHDDD SDSSGESSGD DQDELDLPTY
     KRHKKMEKEA YNDWKSSVLS NKQTKPDPAK PRKQAQLNFK KKPSDMALEV SSAAN
 
 
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