ID   ORF1_VZVD               Reviewed;         108 AA.
AC   P09266;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   23-FEB-2022, entry version 51.
DE   RecName: Full=Structural protein 1;
DE   AltName: Full=Structural ORF1 protein;
GN   ORFNames=ORF1;
OS   Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=10338;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=3018124; DOI=10.1099/0022-1317-67-9-1759;
RA   Davison A.J., Scott J.E.;
RT   "The complete DNA sequence of varicella-zoster virus.";
RL   J. Gen. Virol. 67:1759-1816(1986).
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass type
CC       II membrane protein {ECO:0000250}. Host Golgi apparatus membrane
CC       {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the varicellovirus ORF1 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X04370; CAA27884.1; -; Genomic_DNA.
DR   PIR; A27212; WZBE1.
DR   SMR; P09266; -.
DR   PRIDE; P09266; -.
DR   Proteomes; UP000002602; Genome.
DR   GO; GO:0044178; C:host cell Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Host Golgi apparatus; Host membrane; Membrane; Phosphoprotein;
KW   Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix;
KW   Virion.
FT   CHAIN           1..108
FT                   /note="Structural protein 1"
FT                   /id="PRO_0000116157"
FT   TOPO_DOM        1..77
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        78..98
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        99..108
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000250"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   108 AA;  12104 MW;  FCE40B182831B5CF CRC64;
     MSRVSEYGVP EGVRESDSDT DSVFMYQHTE LMQNNASPLV VQTRPPAVLI PLVDVPRPRS
     RRKASAQLKM QMDRLCNVLG VVLQMATLAL VTYIAFVVHT RATSCKRE