ID   ORF3_AHEV               Reviewed;          87 AA.
AC   Q913Y8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=Protein ORF3;
DE            Short=pORF3;
GN   ORFNames=ORF3;
OS   Avian hepatitis E virus (isolate Chicken/California/Meng) (AHEV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Hepelivirales; Hepeviridae; Orthohepevirus.
OX   NCBI_TaxID=516993;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=11562538; DOI=10.1099/0022-1317-82-10-2449;
RA   Haqshenas G., Shivaprasad H.L., Woolcock P.R., Read D.H., Meng X.J.;
RT   "Genetic identification and characterization of a novel virus related to
RT   human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome
RT   in the United States.";
RL   J. Gen. Virol. 82:2449-2462(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15166445; DOI=10.1099/vir.0.79841-0;
RA   Huang F.F., Sun Z.F., Emerson S.U., Purcell R.H., Shivaprasad H.L.,
RA   Pierson F.W., Toth T.E., Meng X.J.;
RT   "Determination and analysis of the complete genomic sequence of avian
RT   hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with
RT   avian HEV.";
RL   J. Gen. Virol. 85:1609-1618(2004).
CC   -!- FUNCTION: May act as a viral regulatory protein involved in the
CC       modulation of mitogenic signaling pathways. May be involved in virion
CC       morphogenesis and viral pathogenesis (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}.
CC   -!- PTM: Not glycosylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the hepevirus ORF3 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY043166; AAL13368.1; -; Genomic_RNA.
DR   EMBL; AY535004; AAS45832.1; -; Genomic_RNA.
DR   RefSeq; YP_009001466.1; NC_023425.1.
DR   GeneID; 18263427; -.
DR   KEGG; vg:18263427; -.
DR   Proteomes; UP000007439; Genome.
DR   Proteomes; UP000139094; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Host cytoplasm.
FT   CHAIN           1..87
FT                   /note="Protein ORF3"
FT                   /id="PRO_0000334538"
FT   REGION          58..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   87 AA;  9122 MW;  329711739BE48F4D CRC64;
     MCLSCQFWCL ECQESGVGCR CVDCCSCLQC AAGCQGAPKR SQPEAGVASA AVTIQPSGAL
     NNAPREPSAP PLSQTLSPRQ VLARYQM