ID   ORF48_HHV8P             Reviewed;         402 AA.
AC   Q2HR85;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   02-JUN-2021, entry version 43.
DE   RecName: Full=Tegument protein ORF48;
GN   Name=ORF48;
OS   Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's
OS   sarcoma-associated herpesvirus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus.
OX   NCBI_TaxID=868565;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10400794; DOI=10.1128/jvi.73.8.6953-6963.1999;
RA   Glenn M., Rainbow L., Aurade F., Davison A., Schulz T.F.;
RT   "Identification of a spliced gene from Kaposi's sarcoma-associated
RT   herpesvirus encoding a protein with similarities to latent membrane
RT   proteins 1 and 2A of Epstein-Barr virus.";
RL   J. Virol. 73:6953-6963(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16760382; DOI=10.1099/vir.0.81919-0;
RA   Rezaee S.A.R., Cunningham C., Davison A.J., Blackbourn D.J.;
RT   "Kaposi's sarcoma-associated herpesvirus immune modulation: an overview.";
RL   J. Gen. Virol. 87:1781-1804(2006).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}.
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DR   EMBL; AF148805; ABD28898.1; -; Genomic_DNA.
DR   RefSeq; YP_001129400.1; NC_009333.1.
DR   BioGRID; 1776961; 5.
DR   PRIDE; Q2HR85; -.
DR   DNASU; 4961458; -.
DR   GeneID; 4961458; -.
DR   KEGG; vg:4961458; -.
DR   Proteomes; UP000000942; Genome.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008550; Herpesvirus_BRRF2-like.
DR   Pfam; PF05734; DUF832; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..402
FT                   /note="Tegument protein ORF48"
FT                   /id="PRO_0000423797"
SQ   SEQUENCE   402 AA;  44559 MW;  8C4D7FE5ED30E732 CRC64;
     MEVCIPIPGI GDENCESWRA QIVAFGTTSG FVKTERILRG LFPERGHPGF LASLVVLKHT
     LASPGGLNTR LNLLPVLQML KYVGQEMYMR AKCQATASDM TLIWDDCKDR FMLILEQACG
     CHQCMTVVEE ITHCSAISAP PSSLSHGRHI LSAGLINFAR RQVLLGGSVS FSEFSIPDLI
     QTPEQYPFVD VEFRRELSLI SSCLNVCWLY HIFIEHITSD VRRLESCMAS VLEEYGGLSP
     TRPWAEAVTF LSQLPRPTRK PWKELSVSRI NVEARLLDTL VMQLEKPVPV EIIKHALAIL
     GTAGHVWNPE HQLACPDTRT CRERVSKGPC VGDGDVTLVH TARMDISNPS SVSPDGDVHY
     SGPPRTPAYG VVLECADDSD DSLDDFLENL SQTCDSSDDE YD