ID   ORGA_SALTY              Reviewed;         199 AA.
AC   P0CL44; P40823; P58653;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-MAR-2011, sequence version 1.
DT   03-AUG-2022, entry version 38.
DE   RecName: Full=Oxygen-regulated invasion protein OrgA;
GN   Name=orgA; OrderedLocusNames=STM2870;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [2]
RP   CHARACTERIZATION.
RC   STRAIN=SL1344;
RX   PubMed=10816487; DOI=10.1128/iai.68.6.3368-3376.2000;
RA   Klein J.R., Fahlen T.F., Jones B.D.;
RT   "Transcriptional organization and function of invasion genes within
RT   Salmonella enterica serovar Typhimurium pathogenicity island 1, including
RT   the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes.";
RL   Infect. Immun. 68:3368-3376(2000).
CC   -!- FUNCTION: Oxygen-regulated protein required for bacterial
CC       internalization.
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DR   EMBL; AE006468; AAL21750.1; -; Genomic_DNA.
DR   RefSeq; NP_461791.1; NC_003197.2.
DR   RefSeq; WP_001574876.1; NC_003197.2.
DR   AlphaFoldDB; P0CL44; -.
DR   STRING; 99287.STM2870; -.
DR   PaxDb; P0CL44; -.
DR   EnsemblBacteria; AAL21750; AAL21750; STM2870.
DR   GeneID; 1254393; -.
DR   KEGG; stm:STM2870; -.
DR   PATRIC; fig|99287.12.peg.3026; -.
DR   HOGENOM; CLU_092002_0_0_6; -.
DR   OMA; MACQRHR; -.
DR   BioCyc; SENT99287:STM2870-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   InterPro; IPR013388; T3SS_OrgA/MxiK.
DR   Pfam; PF09482; OrgA_MxiK; 1.
DR   TIGRFAMs; TIGR02555; OrgA_MxiK; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Virulence.
FT   CHAIN           1..199
FT                   /note="Oxygen-regulated invasion protein OrgA"
FT                   /id="PRO_0000058082"
SQ   SEQUENCE   199 AA;  22832 MW;  94368148BF784EE3 CRC64;
     MIRRNRQMNR QPLPIIWQRI IFDPLSYIHP QRLQIAPEMI VRPAARAAAN ELILAAWRLK
     NGEKECIQNS LTQLWLRQWR RLPQVAYLLG CHKLRADLAR QGALLGLPDW AQAFLAMHQG
     TSLSVCNKAP NHRFLLSVGY AQLNALNEFL PESLAQRFPL LFPPFIEEAL KQDAVEMSIL
     LLALQYAQKY PNTVPAFAC