ORN_ACTP2
ID ORN_ACTP2 Reviewed; 184 AA.
AC A3N1D8;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN Name=orn {ECO:0000255|HAMAP-Rule:MF_00045}; OrderedLocusNames=APL_1134;
OS Actinobacillus pleuropneumoniae serotype 5b (strain L20).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=416269;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L20;
RX PubMed=18065534; DOI=10.1128/jb.01845-07;
RA Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M.,
RA Nash J.H.E.;
RT "The complete genome sequence of Actinobacillus pleuropneumoniae L20
RT (serotype 5b).";
RL J. Bacteriol. 190:1495-1496(2008).
CC -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR EMBL; CP000569; ABN74224.1; -; Genomic_DNA.
DR RefSeq; WP_005598024.1; NC_009053.1.
DR AlphaFoldDB; A3N1D8; -.
DR SMR; A3N1D8; -.
DR STRING; 416269.APL_1134; -.
DR PRIDE; A3N1D8; -.
DR EnsemblBacteria; ABN74224; ABN74224; APL_1134.
DR GeneID; 66257833; -.
DR KEGG; apl:APL_1134; -.
DR eggNOG; COG1949; Bacteria.
DR HOGENOM; CLU_064761_2_0_6; -.
DR OMA; AFFHYRN; -.
DR Proteomes; UP000001432; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd06135; Orn; 1.
DR Gene3D; 3.30.420.10; -; 1.
DR HAMAP; MF_00045; Oligoribonuclease; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR022894; Oligoribonuclease.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR11046; PTHR11046; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT CHAIN 1..184
FT /note="Oligoribonuclease"
FT /id="PRO_1000004225"
FT DOMAIN 9..172
FT /note="Exonuclease"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT ACT_SITE 130
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
SQ SEQUENCE 184 AA; 21572 MW; 3E68B43DAB8E8B83 CRC64;
MSKLDNQNLI WIDLEMTGLD PEKERIIEVA TIVTDKDLNI LAEGPVLTVH QSNDLLNKMS
DWCIKTHTEN GLIERVKQSK LTERAVELQT IDFLKQWVPK GASPICGNSV AQDKRFLYKY
MPDLADYFHY RHLDVSTLKE LARRWKPDML NAFNKKNTHL ALDDIRESIE ELKFYRTHFI
NLEK