ID   ORN_BIFLO               Reviewed;         216 AA.
AC   Q8G3N5;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE            EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN   Name=orn {ECO:0000255|HAMAP-Rule:MF_00045}; OrderedLocusNames=BL1723;
OS   Bifidobacterium longum (strain NCC 2705).
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=206672;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCC 2705;
RX   PubMed=12381787; DOI=10.1073/pnas.212527599;
RA   Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G.,
RA   Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.;
RT   "The genome sequence of Bifidobacterium longum reflects its adaptation to
RT   the human gastrointestinal tract.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002).
CC   -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC       oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC       {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR   EMBL; AE014295; AAN25507.1; -; Genomic_DNA.
DR   RefSeq; NP_696871.1; NC_004307.2.
DR   RefSeq; WP_007052450.1; NC_004307.2.
DR   AlphaFoldDB; Q8G3N5; -.
DR   SMR; Q8G3N5; -.
DR   STRING; 206672.BL1723; -.
DR   PRIDE; Q8G3N5; -.
DR   EnsemblBacteria; AAN25507; AAN25507; BL1723.
DR   GeneID; 66505782; -.
DR   KEGG; blo:BL1723; -.
DR   PATRIC; fig|206672.9.peg.1778; -.
DR   HOGENOM; CLU_064761_3_0_11; -.
DR   OMA; AFFHYRN; -.
DR   PhylomeDB; Q8G3N5; -.
DR   Proteomes; UP000000439; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd06135; Orn; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   HAMAP; MF_00045; Oligoribonuclease; 1.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR022894; Oligoribonuclease.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR11046; PTHR11046; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..216
FT                   /note="Oligoribonuclease"
FT                   /id="PRO_0000111018"
FT   DOMAIN          17..182
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT   ACT_SITE        139
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
SQ   SEQUENCE   216 AA;  24303 MW;  C4ED2F1DC35F8530 CRC64;
     MVDSHDAETY SAKDSRLIWI DCEMTGLDIF GGDELVEVSV VPTDFDLNVL DEGVDYVIKP
     SEKAVNHMND FVRQMHTRSG LINEWENGLS LAEAEQKVTE YVLRFTPEGV RPLLAGNTIG
     SDKKFLDHYM PNLMSHLHYR SVDVSTFKEL ARRWYPAVYE NRPPKNGGHR ALADIIESLD
     ELRYYRKAFM APAPGPDDAA SKAIAADIVA TSILNK