ORN_COREF
ID ORN_COREF Reviewed; 221 AA.
AC Q8FMX9;
DT 04-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN Name=orn {ECO:0000255|HAMAP-Rule:MF_00045}; OrderedLocusNames=CE2370;
OS Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS / NBRC 100395).
OC Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC Corynebacterium.
OX NCBI_TaxID=196164;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX PubMed=12840036; DOI=10.1101/gr.1285603;
RA Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT "Comparative complete genome sequence analysis of the amino acid
RT replacements responsible for the thermostability of Corynebacterium
RT efficiens.";
RL Genome Res. 13:1572-1579(2003).
CC -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR EMBL; BA000035; BAC19180.1; -; Genomic_DNA.
DR RefSeq; WP_006768376.1; NZ_GG700683.1.
DR AlphaFoldDB; Q8FMX9; -.
DR SMR; Q8FMX9; -.
DR STRING; 196164.23494213; -.
DR EnsemblBacteria; BAC19180; BAC19180; BAC19180.
DR KEGG; cef:CE2370; -.
DR eggNOG; COG1949; Bacteria.
DR HOGENOM; CLU_064761_3_0_11; -.
DR OMA; AFFHYRN; -.
DR OrthoDB; 1390327at2; -.
DR Proteomes; UP000001409; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd06135; Orn; 1.
DR Gene3D; 3.30.420.10; -; 1.
DR HAMAP; MF_00045; Oligoribonuclease; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR022894; Oligoribonuclease.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR11046; PTHR11046; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT CHAIN 1..221
FT /note="Oligoribonuclease"
FT /id="PRO_0000111030"
FT DOMAIN 21..186
FT /note="Exonuclease"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT ACT_SITE 143
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
SQ SEQUENCE 221 AA; 24531 MW; BE7C5DDC36033078 CRC64;
MSETVGNGEN FPAVAARDDR LVWVDLEMTG LDLERHVIVE VAALVTDANL NILGEGVDLV
VHATDEELAR MDDFVTRMHD SSGLTPLIRA STVSLKDAED AVLALIEEHC DPAHPAPLAG
NSIATDRAFI REQMPRLDAA LHYRMVDVSS VKELARRWCP RVYYKQPTKG LAHRALADIV
ESIRELDYYR RSFFVADPGP TSAQCEADAE TSVARFAHYL E