ORN_CORGB
ID ORN_CORGB Reviewed; 219 AA.
AC A4QGM5;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN Name=orn {ECO:0000255|HAMAP-Rule:MF_00045}; OrderedLocusNames=cgR_2384;
OS Corynebacterium glutamicum (strain R).
OC Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC Corynebacterium.
OX NCBI_TaxID=340322;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R;
RX PubMed=17379713; DOI=10.1099/mic.0.2006/003657-0;
RA Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M.,
RA Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.;
RT "Comparative analysis of the Corynebacterium glutamicum group and complete
RT genome sequence of strain R.";
RL Microbiology 153:1042-1058(2007).
CC -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR EMBL; AP009044; BAF55391.1; -; Genomic_DNA.
DR RefSeq; WP_003860849.1; NC_009342.1.
DR AlphaFoldDB; A4QGM5; -.
DR SMR; A4QGM5; -.
DR EnsemblBacteria; BAF55391; BAF55391; cgR_2384.
DR GeneID; 58311119; -.
DR KEGG; cgt:cgR_2384; -.
DR HOGENOM; CLU_064761_3_0_11; -.
DR OMA; AFFHYRN; -.
DR PhylomeDB; A4QGM5; -.
DR Proteomes; UP000006698; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd06135; Orn; 1.
DR Gene3D; 3.30.420.10; -; 1.
DR HAMAP; MF_00045; Oligoribonuclease; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR022894; Oligoribonuclease.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR11046; PTHR11046; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Exonuclease; Hydrolase; Nuclease.
FT CHAIN 1..219
FT /note="Oligoribonuclease"
FT /id="PRO_1000004245"
FT DOMAIN 19..184
FT /note="Exonuclease"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT ACT_SITE 141
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
SQ SEQUENCE 219 AA; 24585 MW; E88990831F54398E CRC64;
MSESENNTTP AVAARDDRLV WVDLEMTGLD LKRHVIVEVA ALVTDANLNV LGEGVDLVVH
ATEEELAQMD DFVTNMHESS GLTEQIRESA VTLKEAEDAV LALIEKHCDP AHPAPLAGNS
IATDRAFIRE QMPRLDEALH YRMVDVSSVK ELARRWYPRV YYKQPEKGLA HRALADIVES
IRELDYYRRS FFVAEPGPTS EQCADDAQAA VDRFAPYFD