ID   ORN_COXBU               Reviewed;         183 AA.
AC   Q83C93;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE            EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN   Name=orn {ECO:0000255|HAMAP-Rule:MF_00045}; OrderedLocusNames=CBU_1235;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
CC   -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC       oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC       {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR   EMBL; AE016828; AAO90744.1; -; Genomic_DNA.
DR   RefSeq; NP_820230.1; NC_002971.3.
DR   RefSeq; WP_005770781.1; NZ_CDBG01000001.1.
DR   PDB; 3TR8; X-ray; 2.50 A; A/B=1-183.
DR   PDBsum; 3TR8; -.
DR   AlphaFoldDB; Q83C93; -.
DR   SMR; Q83C93; -.
DR   STRING; 227377.CBU_1235; -.
DR   DNASU; 1209140; -.
DR   EnsemblBacteria; AAO90744; AAO90744; CBU_1235.
DR   GeneID; 1209140; -.
DR   KEGG; cbu:CBU_1235; -.
DR   PATRIC; fig|227377.7.peg.1227; -.
DR   eggNOG; COG1949; Bacteria.
DR   HOGENOM; CLU_064761_2_0_6; -.
DR   OMA; AFFHYRN; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd06135; Orn; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   HAMAP; MF_00045; Oligoribonuclease; 1.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR022894; Oligoribonuclease.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR11046; PTHR11046; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Exonuclease; Hydrolase; Nuclease;
KW   Reference proteome.
FT   CHAIN           1..183
FT                   /note="Oligoribonuclease"
FT                   /id="PRO_0000111032"
FT   DOMAIN          8..171
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT   ACT_SITE        129
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT   STRAND          8..18
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   TURN            20..22
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   STRAND          25..33
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   STRAND          39..42
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           52..55
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           60..68
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           71..76
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           82..93
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   TURN            94..96
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   STRAND          104..108
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           110..119
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           121..126
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   STRAND          131..133
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           134..144
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           146..149
FT                   /evidence="ECO:0007829|PDB:3TR8"
FT   HELIX           160..177
FT                   /evidence="ECO:0007829|PDB:3TR8"
SQ   SEQUENCE   183 AA;  21012 MW;  5DE66FF76A607680 CRC64;
     MDFSDDNLIW LDLEMTGLDP ERDRIIEIAT IVTNSHLDIL AEGPAFAIHQ PDKLLTAMDN
     WNTSHHTASG LLERVKNSSV DEVEAETLTL AFLEKYVSAG KSPLCGNSVC QDRRFLSRYM
     PRLNQFFHYR HLDVTTLKIL AQRWAPQIAA AHIKESQHLA LQDIRDSIEE LRYYRAHLLN
     LSK