ID   ORN_PSEAE               Reviewed;         180 AA.
AC   P57665;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE            EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN   Name=orn {ECO:0000255|HAMAP-Rule:MF_00045}; OrderedLocusNames=PA4951;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC       oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC       {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR   EMBL; AE004091; AAG08336.1; -; Genomic_DNA.
DR   PIR; E83026; E83026.
DR   RefSeq; NP_253638.1; NC_002516.2.
DR   RefSeq; WP_003095671.1; NZ_QZGE01000002.1.
DR   AlphaFoldDB; P57665; -.
DR   SMR; P57665; -.
DR   STRING; 287.DR97_2304; -.
DR   PaxDb; P57665; -.
DR   PRIDE; P57665; -.
DR   EnsemblBacteria; AAG08336; AAG08336; PA4951.
DR   GeneID; 878205; -.
DR   KEGG; pae:PA4951; -.
DR   PATRIC; fig|208964.12.peg.5184; -.
DR   PseudoCAP; PA4951; -.
DR   HOGENOM; CLU_064761_2_0_6; -.
DR   InParanoid; P57665; -.
DR   OMA; AFFHYRN; -.
DR   PhylomeDB; P57665; -.
DR   BioCyc; PAER208964:G1FZ6-5067-MON; -.
DR   BRENDA; 3.1.13.3; 5087.
DR   PHI-base; PHI:6274; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd06135; Orn; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   HAMAP; MF_00045; Oligoribonuclease; 1.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR022894; Oligoribonuclease.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR11046; PTHR11046; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..180
FT                   /note="Oligoribonuclease"
FT                   /id="PRO_0000111061"
FT   DOMAIN          7..170
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT   ACT_SITE        128
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
SQ   SEQUENCE   180 AA;  20827 MW;  E66C00A72AA120D2 CRC64;
     MQNPQNLIWI DLEMTGLDPD RDVIIEMATI VTDSDLNTLA EGPVIAIHQP EEILAGMDEW
     NTRQHGQSGL TQRVRESTVS MAEAEAQTLA FLEQWVPKRS SPICGNSICQ DRRFLYRHMP
     RLEGYFHYRN LDVSTLKELA ARWAPQVRES FKKGNTHLAL DDIRESIAEL RHYRDHFIKL