ID   ORN_VIBC3               Reviewed;         181 AA.
AC   A5F3M7; C3M3Z9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE            EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN   Name=orn {ECO:0000255|HAMAP-Rule:MF_00045};
GN   OrderedLocusNames=VC0395_A2743, VC395_0384;
OS   Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS   O395).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=345073;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA   Heidelberg J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC       oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC   -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC       {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR   EMBL; CP000627; ABQ19537.1; -; Genomic_DNA.
DR   EMBL; CP001235; ACP08407.1; -; Genomic_DNA.
DR   RefSeq; WP_000010183.1; NZ_JAACZH010000036.1.
DR   PDB; 6N6A; X-ray; 1.50 A; A=1-181.
DR   PDB; 6N6C; X-ray; 1.62 A; A=1-181.
DR   PDBsum; 6N6A; -.
DR   PDBsum; 6N6C; -.
DR   AlphaFoldDB; A5F3M7; -.
DR   SMR; A5F3M7; -.
DR   STRING; 345073.VC395_0384; -.
DR   PRIDE; A5F3M7; -.
DR   EnsemblBacteria; ABQ19537; ABQ19537; VC0395_A2743.
DR   KEGG; vco:VC0395_A2743; -.
DR   KEGG; vcr:VC395_0384; -.
DR   PATRIC; fig|345073.21.peg.372; -.
DR   eggNOG; COG1949; Bacteria.
DR   HOGENOM; CLU_064761_2_0_6; -.
DR   OMA; AFFHYRN; -.
DR   Proteomes; UP000000249; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd06135; Orn; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   HAMAP; MF_00045; Oligoribonuclease; 1.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR022894; Oligoribonuclease.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR11046; PTHR11046; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Exonuclease; Hydrolase; Nuclease.
FT   CHAIN           1..181
FT                   /note="Oligoribonuclease"
FT                   /id="PRO_1000071091"
FT   DOMAIN          8..171
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT   ACT_SITE        129
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT   STRAND          8..18
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   TURN            20..22
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   STRAND          25..33
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   STRAND          39..47
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           52..55
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           60..68
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           71..77
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           82..93
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   TURN            94..96
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   TURN            99..101
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   STRAND          104..108
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           109..119
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           121..124
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   STRAND          131..133
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           134..144
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           146..151
FT                   /evidence="ECO:0007829|PDB:6N6A"
FT   HELIX           160..177
FT                   /evidence="ECO:0007829|PDB:6N6A"
SQ   SEQUENCE   181 AA;  20929 MW;  AAC071B9C94FEFE3 CRC64;
     MSFSDQNLIW IDLEMTGLDP EMHKIIEMAT IVTDSELNIL AEGPVIAIHQ PESELAKMDE
     WCTTTHTASG LVARVRQSQV SEEEAIDQTL AFLKQWVPEG KSPICGNSIG QDRRFLYKHM
     PRLEAYFHYR YIDVSTIKEL TRRWQPEVLK EFSKTGSHLA LDDIRESIAE LQFYRKAVFK
     I