ORN_YERE8
ID ORN_YERE8 Reviewed; 181 AA.
AC A1JIQ8;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Oligoribonuclease {ECO:0000255|HAMAP-Rule:MF_00045};
DE EC=3.1.15.- {ECO:0000255|HAMAP-Rule:MF_00045};
GN Name=orn {ECO:0000255|HAMAP-Rule:MF_00045}; OrderedLocusNames=YE0369;
OS Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS 8081).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=393305;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 13174 / 8081;
RX PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA Prentice M.B.;
RT "The complete genome sequence and comparative genome analysis of the high
RT pathogenicity Yersinia enterocolitica strain 8081.";
RL PLoS Genet. 2:2039-2051(2006).
CC -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC oligoribonucleotides. {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00045}.
CC -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC {ECO:0000255|HAMAP-Rule:MF_00045}.
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DR EMBL; AM286415; CAL10499.1; -; Genomic_DNA.
DR RefSeq; WP_011815420.1; NC_008800.1.
DR RefSeq; YP_001004745.1; NC_008800.1.
DR AlphaFoldDB; A1JIQ8; -.
DR SMR; A1JIQ8; -.
DR STRING; 393305.YE0369; -.
DR PRIDE; A1JIQ8; -.
DR EnsemblBacteria; CAL10499; CAL10499; YE0369.
DR GeneID; 67419294; -.
DR KEGG; yen:YE0369; -.
DR PATRIC; fig|393305.7.peg.466; -.
DR eggNOG; COG1949; Bacteria.
DR HOGENOM; CLU_064761_2_0_6; -.
DR OMA; AFFHYRN; -.
DR Proteomes; UP000000642; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd06135; Orn; 1.
DR Gene3D; 3.30.420.10; -; 1.
DR HAMAP; MF_00045; Oligoribonuclease; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR022894; Oligoribonuclease.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR11046; PTHR11046; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Exonuclease; Hydrolase; Nuclease.
FT CHAIN 1..181
FT /note="Oligoribonuclease"
FT /id="PRO_1000004300"
FT DOMAIN 8..171
FT /note="Exonuclease"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
FT ACT_SITE 129
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00045"
SQ SEQUENCE 181 AA; 20958 MW; 91BC155CA8ED3426 CRC64;
MAENQNNLIW IDLEMTGLDP ERDRIIEIAT LVTDANLNIL AEGPVLAVHQ SDEQLGLMDE
WNVRTHTGSG LVERVKASPF NDHDAELQTI EFLKQWVPAG TSPICGNSVG QDRRFLFRYM
PELEAYFHYR YLDVSTLKEL ARRWKPEILA GFKKQNTHQA LDDIRESVAE LAYYREHFIQ
K