ID   ORP1B_ARATH             Reviewed;         489 AA.
AC   Q8S8P9;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Oxysterol-binding protein-related protein 1B;
DE   AltName: Full=OSBP-related protein 1B;
GN   Name=ORP1B; OrderedLocusNames=At2g31030; ORFNames=F7F1.24;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16897474; DOI=10.1007/s11103-006-0030-y;
RA   Skirpan A.L., Dowd P.E., Sijacic P., Jaworski C.J., Gilroy S., Kao T.H.;
RT   "Identification and characterization of PiORP1, a Petunia oxysterol-
RT   binding-protein related protein involved in receptor-kinase mediated
RT   signaling in pollen, and analysis of the ORP gene family in Arabidopsis.";
RL   Plant Mol. Biol. 61:553-565(2006).
CC   -!- FUNCTION: May be involved in the transport of sterols. {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed at low levels in flowers.
CC       {ECO:0000269|PubMed:16897474}.
CC   -!- SIMILARITY: Belongs to the OSBP family. {ECO:0000305}.
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DR   EMBL; AC004669; AAM14977.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC08480.1; -; Genomic_DNA.
DR   PIR; F84715; F84715.
DR   RefSeq; NP_180660.1; NM_128657.1.
DR   AlphaFoldDB; Q8S8P9; -.
DR   SMR; Q8S8P9; -.
DR   STRING; 3702.AT2G31030.1; -.
DR   PaxDb; Q8S8P9; -.
DR   PRIDE; Q8S8P9; -.
DR   EnsemblPlants; AT2G31030.1; AT2G31030.1; AT2G31030.
DR   GeneID; 817654; -.
DR   Gramene; AT2G31030.1; AT2G31030.1; AT2G31030.
DR   KEGG; ath:AT2G31030; -.
DR   Araport; AT2G31030; -.
DR   TAIR; locus:2052816; AT2G31030.
DR   eggNOG; KOG1737; Eukaryota.
DR   HOGENOM; CLU_007105_0_0_1; -.
DR   InParanoid; Q8S8P9; -.
DR   OMA; MWISNGK; -.
DR   OrthoDB; 542090at2759; -.
DR   PhylomeDB; Q8S8P9; -.
DR   PRO; PR:Q8S8P9; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8S8P9; baseline and differential.
DR   Genevisible; Q8S8P9; AT.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0032934; F:sterol binding; IBA:GO_Central.
DR   GO; GO:0015248; F:sterol transporter activity; IBA:GO_Central.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   PANTHER; PTHR10972; PTHR10972; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   SUPFAM; SSF144000; SSF144000; 1.
PE   2: Evidence at transcript level;
KW   Lipid transport; Lipid-binding; Reference proteome; Transport.
FT   CHAIN           1..489
FT                   /note="Oxysterol-binding protein-related protein 1B"
FT                   /id="PRO_0000402157"
SQ   SEQUENCE   489 AA;  56556 MW;  EC3EC44B924C5E89 CRC64;
     MEARVISCTT FGDNKVVKIA VLNHQAITKY KAGENETTVV VSDDTCPEKD VKEIKKFCEK
     LGYVYEGRLS EEYTQTNTGP DDDWITNGFE SDDDVDPSIK TIGFNYPHVN RRNKLPDPVE
     KEKSVSLWSM IKDNIGKDLT KVCLPVYFNE PLSSLQKCFE DLEYSYLLDQ ASEWGKRGNN
     LMRILNVAAF AVSGYASTKG RICKPFNPML GETYEADYPD KGLRFFSEKV SHHPMIVACH
     CDGTGWKFWG DSNLKSKFWG RSIQLDPIGL LTLQFDDGEI VQWSKVTTSI YNLILGKLYC
     DHYGTMLIEG NGEYSCKLKF KKQSMMDRNP HQVQGIVEDK NGKTVAKLFG KWDESMYYVM
     VNQGKESESH LLWKRNKPLE NPTKYNLTRF GITLNELTPD LKEMLPPTDS RLRPDQRYLE
     KGEFEMGNRE KLRLEQRQRQ AREKQERGWK PTWFSKEKGS ETYRYIGGYW EARDSGRWDD
     CPDIFGQVH