ID   ORP4C_ARATH             Reviewed;         379 AA.
AC   Q9LVD4;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Oxysterol-binding protein-related protein 4C;
DE   AltName: Full=OSBP-related protein 4C;
GN   Name=ORP4C; OrderedLocusNames=At5g57240; ORFNames=MJB24.5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [4]
RP   TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16897474; DOI=10.1007/s11103-006-0030-y;
RA   Skirpan A.L., Dowd P.E., Sijacic P., Jaworski C.J., Gilroy S., Kao T.H.;
RT   "Identification and characterization of PiORP1, a Petunia oxysterol-
RT   binding-protein related protein involved in receptor-kinase mediated
RT   signaling in pollen, and analysis of the ORP gene family in Arabidopsis.";
RL   Plant Mol. Biol. 61:553-565(2006).
CC   -!- FUNCTION: May be involved in the transport of sterols. {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in flowers.
CC       {ECO:0000269|PubMed:16897474}.
CC   -!- SIMILARITY: Belongs to the OSBP family. {ECO:0000305}.
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DR   EMBL; AB019233; BAA96947.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED96869.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED96870.1; -; Genomic_DNA.
DR   EMBL; CP002688; ANM68212.1; -; Genomic_DNA.
DR   EMBL; AK117264; BAC41939.1; -; mRNA.
DR   RefSeq; NP_001032088.1; NM_001037011.2.
DR   RefSeq; NP_001329985.1; NM_001345252.1.
DR   RefSeq; NP_200534.1; NM_125106.3.
DR   AlphaFoldDB; Q9LVD4; -.
DR   SMR; Q9LVD4; -.
DR   STRING; 3702.AT5G57240.2; -.
DR   PaxDb; Q9LVD4; -.
DR   ProteomicsDB; 248738; -.
DR   EnsemblPlants; AT5G57240.1; AT5G57240.1; AT5G57240.
DR   EnsemblPlants; AT5G57240.2; AT5G57240.2; AT5G57240.
DR   EnsemblPlants; AT5G57240.5; AT5G57240.5; AT5G57240.
DR   GeneID; 835830; -.
DR   Gramene; AT5G57240.1; AT5G57240.1; AT5G57240.
DR   Gramene; AT5G57240.2; AT5G57240.2; AT5G57240.
DR   Gramene; AT5G57240.5; AT5G57240.5; AT5G57240.
DR   KEGG; ath:AT5G57240; -.
DR   Araport; AT5G57240; -.
DR   TAIR; locus:2165575; AT5G57240.
DR   eggNOG; KOG2210; Eukaryota.
DR   HOGENOM; CLU_044270_0_0_1; -.
DR   InParanoid; Q9LVD4; -.
DR   PhylomeDB; Q9LVD4; -.
DR   PRO; PR:Q9LVD4; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LVD4; baseline and differential.
DR   Genevisible; Q9LVD4; AT.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0032934; F:sterol binding; IBA:GO_Central.
DR   GO; GO:0015248; F:sterol transporter activity; IBA:GO_Central.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   InterPro; IPR018494; Oxysterol-bd_CS.
DR   PANTHER; PTHR10972; PTHR10972; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   SUPFAM; SSF144000; SSF144000; 1.
DR   PROSITE; PS01013; OSBP; 1.
PE   2: Evidence at transcript level;
KW   Lipid transport; Lipid-binding; Reference proteome; Transport.
FT   CHAIN           1..379
FT                   /note="Oxysterol-binding protein-related protein 4C"
FT                   /id="PRO_0000402167"
SQ   SEQUENCE   379 AA;  42968 MW;  2699361D5DBD9674 CRC64;
     MKKHVMLVKP FSLEDEKDSE NTPPNLIQRI LSLFKNVRPG SDLTNFQLPP QMNLARSQLQ
     CYGEIVYSFD GHDLLGECSR RDKPIERMKA MVTWYISTLR PLIFGLAPYN PVIGETHHVS
     NGHINVLAEQ ISHHPPVSAL HATHEKENVD VLLCQYFTPK FRGAYVDVEV KGKRVVKLLN
     HKETYEMNQP KLLMTFLPAM GAHWAGKIVI KCPETGLGAE LQLLSDSFLS RFTGNNKRAI
     KGKIFESSSR KQLYEISGHW DRTVTAKNTK TGQLEVIYKA SENIAKLKTP IVENLQEVSE
     SESAVVWGEV SEGIVTNNWE KAREAKRDVE EKQRESLRKR KASGQSWIPK HFSVARTGKD
     WDCVPLQPTV PRAPIVVPL