ID   ORPO_POTOR              Reviewed;           9 AA.
AC   P85159;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 1.
DT   26-FEB-2020, entry version 22.
DE   RecName: Full=Orpotrin;
OS   Potamotrygon orbignyi (Smooth back river stingray).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Batoidea; Myliobatiformes; Potamotrygonidae; Potamotrygon.
OX   NCBI_TaxID=86381;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND
RP   MASS SPECTROMETRY.
RC   TISSUE=Venom {ECO:0000269|PubMed:17056153};
RX   PubMed=17056153; DOI=10.1016/j.peptides.2006.09.002;
RA   Conceicao K., Konno K., Melo R.L., Marques E.E., Hiruma-Lima C.A., Lima C.,
RA   Richardson M., Pimenta D.C., Lopes-Ferreira M.;
RT   "Orpotrin: a novel vasoconstrictor peptide from the venom of the Brazilian
RT   stingray Potamotrygon gr. orbignyi.";
RL   Peptides 27:3039-3046(2006).
CC   -!- FUNCTION: Vasoconstrictor. {ECO:0000269|PubMed:17056153}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17056153}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000269|PubMed:17056153}.
CC   -!- MASS SPECTROMETRY: Mass=1002.55; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:17056153};
CC   -!- MASS SPECTROMETRY: Mass=1002.046; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:17056153};
CC   -!- MISCELLANEOUS: May be produced from creatine kinase by limited
CC       proteolysis. {ECO:0000269|PubMed:17056153}.
CC   -!- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
CC       {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0042310; P:vasoconstriction; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted; Toxin; Vasoactive; Vasoconstrictor.
FT   PEPTIDE         1..9
FT                   /note="Orpotrin"
FT                   /evidence="ECO:0000269|PubMed:17056153"
FT                   /id="PRO_0000292606"
SQ   SEQUENCE   9 AA;  1002 MW;  2352B1B7632B5878 CRC64;
     HGGYKPTDK