ID   ORR22_ORYSI             Reviewed;         696 AA.
AC   B8B3I4;
DT   16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Two-component response regulator ORR22 {ECO:0000305};
GN   Name=RR22 {ECO:0000305}; ORFNames=OsI_21925 {ECO:0000312|EMBL:EEC80137.1};
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Transcriptional activator that binds specific DNA sequence.
CC       Functions as a response regulator involved in His-to-Asp phosphorelay
CC       signal transduction system. Phosphorylation of the Asp residue in the
CC       receiver domain activates the ability of the protein to promote the
CC       transcription of target genes. May directly activate some type-A
CC       response regulators in response to cytokinins.
CC       {ECO:0000250|UniProtKB:Q940D0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC   -!- PTM: Two-component system major event consists of a His-to-Asp
CC       phosphorelay between a sensor histidine kinase (HK) and a response
CC       regulator (RR). In plants, the His-to-Asp phosphorelay involves an
CC       additional intermediate named Histidine-containing phosphotransfer
CC       protein (HPt). This multistep phosphorelay consists of a His-Asp-His-
CC       Asp sequential transfer of a phosphate group between first an His and
CC       an Asp of the HK protein, followed by the transfer to a conserved His
CC       of the HPt protein and finally the transfer to an Asp in the receiver
CC       domain of the RR protein. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ARR family. Type-B subfamily. {ECO:0000305}.
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DR   EMBL; CM000131; EEC80137.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8B3I4; -.
DR   SMR; B8B3I4; -.
DR   STRING; 39946.B8B3I4; -.
DR   PRIDE; B8B3I4; -.
DR   EnsemblPlants; BGIOSGA022430-TA; BGIOSGA022430-PA; BGIOSGA022430.
DR   Gramene; BGIOSGA022430-TA; BGIOSGA022430-PA; BGIOSGA022430.
DR   HOGENOM; CLU_024359_0_0_1; -.
DR   OMA; IASHCAG; -.
DR   Proteomes; UP000007015; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:EnsemblPlants.
DR   GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:EnsemblPlants.
DR   InterPro; IPR045279; ARR-like.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017930; Myb_dom.
DR   InterPro; IPR006447; Myb_dom_plants.
DR   InterPro; IPR017053; Response_reg_B-typ_pln.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43874; PTHR43874; 1.
DR   Pfam; PF00249; Myb_DNA-binding; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PIRSF; PIRSF036392; RR_ARR_type-B; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR   PROSITE; PS51294; HTH_MYB; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; Cytokinin signaling pathway; DNA-binding; Nucleus;
KW   Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..696
FT                   /note="Two-component response regulator ORR22"
FT                   /id="PRO_0000433843"
FT   DOMAIN          27..142
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        214..273
FT                   /note="Myb-like GARP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   REGION          154..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..183
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         78
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   696 AA;  75923 MW;  1741E7D9A1146CAC CRC64;
     MLLGALRMEE RKGLMGRERD QFPVGMRVLA VDDDPVCLKV LETLLRRCQY HVTSTNQAIT
     ALKLLRENRD MFDLVISDVH MPDMDGFKLL ELVGLEMDLP VIMLSVNGET KTVMKGITHG
     ACDYLLKPVR IEELRNIWQH VVRRKFGNRE RNNLDFSKEC NKPQSADTDH GPYQPTCGSS
     DQNGRSSRKR KELHGEDDDE GDDNDYQEND EPSAAKKPRV VWSVELHRKF VAAVNQLGID
     KAVPKRILEL MNVEKLTREN VASHLQKYRL YLKRLGAVAS QQASIVAAFG GRDPSFLHIG
     AFEGLQSYQP FAPSAALPSF NPHGLLTRTS AAAAFGLQEL AAPSSTIQTS TGNVTVGHCL
     EENQQANLAQ GLTAAIGQPQ LQQNWIHQEG NGLSDVFSGS SLTNTLSSTL QRVPSSSLPP
     QELLECKQAK VSMPPSIRIP PSSSALLERT LGVSTNLGDS SISQQGALPI DGGFSADRLP
     LHSSFDGAVA TKLDTSLAAS QREIGQQGKF SVSMLVSPSD NLALAKNAKT GASSSGSTII
     LPLDTARHSD YLQFGGASNS LQKMDGQKQD HIQSSNIIWS SMPSTQLPSD TQIHNTQSQR
     LDSGSFNHNI GAHLADQTNA SASILPQMKF DTRISEEKMK QKNTYDLGSS KLQGGFNSSG
     CNFDGLLNSI IKVEKDDLPF MDNELGCDLF PLGACI