ORR22_ORYSJ
ID ORR22_ORYSJ Reviewed; 696 AA.
AC Q5SML5; A0A0P0WTP4;
DT 16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Two-component response regulator ORR22 {ECO:0000305};
DE AltName: Full=OsRRB4 {ECO:0000303|PubMed:16891544};
GN Name=RR22 {ECO:0000303|PubMed:17284581};
GN Synonyms=ORR2 {ECO:0000303|PubMed:16919402};
GN OrderedLocusNames=Os06g0183100 {ECO:0000312|EMBL:BAF18900.1},
GN LOC_Os06g08440 {ECO:0000305};
GN ORFNames=OsJ_20357 {ECO:0000312|EMBL:EEE65213.1},
GN OSJNBb0036B04.15 {ECO:0000312|EMBL:BAD72541.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16919402; DOI=10.1016/j.gene.2006.06.020;
RA Ito Y., Kurata N.;
RT "Identification and characterization of cytokinin-signalling gene families
RT in rice.";
RL Gene 382:57-65(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP DISRUPTION PHENOTYPE.
RX PubMed=16891544; DOI=10.1104/pp.106.086371;
RA Pareek A., Singh A., Kumar M., Kushwaha H.R., Lynn A.M.,
RA Singla-Pareek S.L.;
RT "Whole-genome analysis of Oryza sativa reveals similar architecture of two-
RT component signaling machinery with Arabidopsis.";
RL Plant Physiol. 142:380-397(2006).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17284581; DOI=10.1104/pp.106.093666;
RA Schaller G.E., Doi K., Hwang I., Kieber J.J., Khurana J.P., Kurata N.,
RA Mizuno T., Pareek A., Shiu S.H., Wu P., Yip W.K.;
RT "Nomenclature for two-component signaling elements of rice.";
RL Plant Physiol. 143:555-557(2007).
RN [9]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=22383541; DOI=10.1104/pp.111.192765;
RA Tsai Y.C., Weir N.R., Hill K., Zhang W., Kim H.J., Shiu S.H.,
RA Schaller G.E., Kieber J.J.;
RT "Characterization of genes involved in cytokinin signaling and metabolism
RT from rice.";
RL Plant Physiol. 158:1666-1684(2012).
CC -!- FUNCTION: Transcriptional activator that binds specific DNA sequence.
CC Functions as a response regulator involved in His-to-Asp phosphorelay
CC signal transduction system. Phosphorylation of the Asp residue in the
CC receiver domain activates the ability of the protein to promote the
CC transcription of target genes. May directly activate some type-A
CC response regulators in response to cytokinins (By similarity).
CC Functions as a response regulator in response to cytokinins
CC (PubMed:22383541). {ECO:0000250|UniProtKB:Q940D0,
CC ECO:0000269|PubMed:22383541}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000269|PubMed:22383541}.
CC -!- PTM: Two-component system major event consists of a His-to-Asp
CC phosphorelay between a sensor histidine kinase (HK) and a response
CC regulator (RR). In plants, the His-to-Asp phosphorelay involves an
CC additional intermediate named Histidine-containing phosphotransfer
CC protein (HPt). This multistep phosphorelay consists of a His-Asp-His-
CC Asp sequential transfer of a phosphate group between first an His and
CC an Asp of the HK protein, followed by the transfer to a conserved His
CC of the HPt protein and finally the transfer to an Asp in the receiver
CC domain of the RR protein. {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: Dwarf, narrow leaf, lesion mimic, low tillering,
CC late heading and low fertility phenotypes.
CC {ECO:0000269|PubMed:16891544}.
CC -!- SIMILARITY: Belongs to the ARR family. Type-B subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BR000251; FAA00255.1; -; Genomic_DNA.
DR EMBL; AP007226; BAD72541.1; -; Genomic_DNA.
DR EMBL; AP008212; BAF18900.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS96483.1; -; Genomic_DNA.
DR EMBL; CM000143; EEE65213.1; -; Genomic_DNA.
DR EMBL; AK102959; BAG95803.1; -; mRNA.
DR RefSeq; XP_015640894.1; XM_015785408.1.
DR AlphaFoldDB; Q5SML5; -.
DR SMR; Q5SML5; -.
DR STRING; 4530.OS06T0183100-01; -.
DR PaxDb; Q5SML5; -.
DR PRIDE; Q5SML5; -.
DR EnsemblPlants; Os06t0183100-01; Os06t0183100-01; Os06g0183100.
DR EnsemblPlants; Os06t0183100-02; Os06t0183100-02; Os06g0183100.
DR GeneID; 4340320; -.
DR Gramene; Os06t0183100-01; Os06t0183100-01; Os06g0183100.
DR Gramene; Os06t0183100-02; Os06t0183100-02; Os06g0183100.
DR KEGG; osa:4340320; -.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_024359_0_0_1; -.
DR InParanoid; Q5SML5; -.
DR OMA; IASHCAG; -.
DR OrthoDB; 332559at2759; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000007752; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR Genevisible; Q5SML5; OS.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR GO; GO:0009736; P:cytokinin-activated signaling pathway; IDA:UniProtKB.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IDA:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR InterPro; IPR045279; ARR-like.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR017053; Response_reg_B-typ_pln.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43874; PTHR43874; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PIRSF; PIRSF036392; RR_ARR_type-B; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 2: Evidence at transcript level;
KW Activator; Cytokinin signaling pathway; DNA-binding; Nucleus;
KW Phosphoprotein; Reference proteome; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1..696
FT /note="Two-component response regulator ORR22"
FT /id="PRO_0000433842"
FT DOMAIN 27..142
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DNA_BIND 214..273
FT /note="Myb-like GARP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 154..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 78
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 696 AA; 75950 MW; 86F8F72741FA624C CRC64;
MLLGALRMEE RKGLMGRERD QFPVGMRVLA VDDDPVCLKV LETLLRRCQY HVTSTNQAIT
ALKLLRENRD MFDLVISDVH MPDMDGFKLL ELVGLEMDLP VIMLSVNGET KTVMKGITHG
ACDYLLKPVR IEELRNIWQH VVRRKFGNRE RNNLDFSKEC NKPQSADTDH GPYQPTCGSS
DQNGRSSRKR KELHGEDDDE GDDNDYQEND EPSAAKKPRV VWSVELHRKF VAAVNQLGID
KAVPKRILEL MNVEKLTREN VASHLQKYRL YLKRLGAVAS QQASIVAAFG GRDPSFLHIG
AFEGLQSYQP FAPSAALPSF NPHGLLTRTS AAAAFGLQEL AAPSSTIQTS TGNVTVGHCL
EENQQANLAQ GLTAAIGQPQ LQQNWIHQEG NGLSDVFSGS SLTNTLSSTL QRVPSSSLPP
QELLECKQAK VSMPPSIRIP PSSSALLERT LGVSTNLGDS SISQQGALPI DGGFSADRLP
LHSSFDGAVA TKLDTSLAAS QREIGQQGKF SVSMLVSPSD NLALAKNAKT GASSSGSTII
LPLDTARHSD YLQFGGASNS LQKMDGQKQD HIQSSNIIWS SMPSTQLPSD TQIHNTQNQR
LDSGSFNHNI GAHLADQTNA SASILPQMKF DTRISEEKMK QKNTYDLGSS KLQGGFNSSG
CNFDGLLNSI IKVEKDDLPF MDNELGCDLF PLGACI
