ID   ORR3_ORYSJ              Reviewed;         131 AA.
AC   Q6K9T0; A0A0P0VRN9;
DT   16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Two-component response regulator ORR3 {ECO:0000305};
DE   AltName: Full=OsRR3 {ECO:0000303|PubMed:16919402};
DE   AltName: Full=OsRRA7 {ECO:0000303|PubMed:16891544};
GN   Name=RR3 {ECO:0000303|PubMed:17284581};
GN   OrderedLocusNames=Os02g0830200 {ECO:0000312|EMBL:BAF10527.1},
GN   LOC_Os02g58350 {ECO:0000305};
GN   ORFNames=OJ1124_D06.19 {ECO:0000312|EMBL:BAD22948.1},
GN   OsJ_08987 {ECO:0000312|EMBL:EAZ25187.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16919402; DOI=10.1016/j.gene.2006.06.020;
RA   Ito Y., Kurata N.;
RT   "Identification and characterization of cytokinin-signalling gene families
RT   in rice.";
RL   Gene 382:57-65(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=17293362; DOI=10.1093/pcp/pcm022;
RA   Hirose N., Makita N., Kojima M., Kamada-Nobusada T., Sakakibara H.;
RT   "Overexpression of a type-A response regulator alters rice morphology and
RT   cytokinin metabolism.";
RL   Plant Cell Physiol. 48:523-539(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [7]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=16891544; DOI=10.1104/pp.106.086371;
RA   Pareek A., Singh A., Kumar M., Kushwaha H.R., Lynn A.M.,
RA   Singla-Pareek S.L.;
RT   "Whole-genome analysis of Oryza sativa reveals similar architecture of two-
RT   component signaling machinery with Arabidopsis.";
RL   Plant Physiol. 142:380-397(2006).
RN   [8]
RP   INDUCTION BY CYTOKININ.
RX   PubMed=17408920; DOI=10.1016/j.ygeno.2007.02.001;
RA   Du L., Jiao F., Chu J., Jin G., Chen M., Wu P.;
RT   "The two-component signal system in rice (Oryza sativa L.): a genome-wide
RT   study of cytokinin signal perception and transduction.";
RL   Genomics 89:697-707(2007).
RN   [9]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17284581; DOI=10.1104/pp.106.093666;
RA   Schaller G.E., Doi K., Hwang I., Kieber J.J., Khurana J.P., Kurata N.,
RA   Mizuno T., Pareek A., Shiu S.H., Wu P., Yip W.K.;
RT   "Nomenclature for two-component signaling elements of rice.";
RL   Plant Physiol. 143:555-557(2007).
RN   [10]
RP   SUBCELLULAR LOCATION.
RX   PubMed=22383541; DOI=10.1104/pp.111.192765;
RA   Tsai Y.C., Weir N.R., Hill K., Zhang W., Kim H.J., Shiu S.H.,
RA   Schaller G.E., Kieber J.J.;
RT   "Characterization of genes involved in cytokinin signaling and metabolism
RT   from rice.";
RL   Plant Physiol. 158:1666-1684(2012).
CC   -!- FUNCTION: Functions as response regulator involved in His-to-Asp
CC       phosphorelay signal transduction system. Phosphorylation of the Asp
CC       residue in the receiver domain activates the ability of the protein to
CC       promote the transcription of target genes. Type-A response regulators
CC       seem to act as negative regulators of the cytokinin signaling.
CC       {ECO:0000250|UniProtKB:Q9ZWS9}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:22383541}.
CC       Nucleus {ECO:0000269|PubMed:22383541}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, leaf blades, leaf sheaths,
CC       shoot apex, flowers and panicles. {ECO:0000269|PubMed:16919402}.
CC   -!- INDUCTION: By cytokinin in roots and leaves.
CC       {ECO:0000269|PubMed:17408920}.
CC   -!- PTM: Two-component system major event consists of a His-to-Asp
CC       phosphorelay between a sensor histidine kinase (HK) and a response
CC       regulator (RR). In plants, the His-to-Asp phosphorelay involves an
CC       additional intermediate named Histidine-containing phosphotransfer
CC       protein (HPt). This multistep phosphorelay consists of a His-Asp-His-
CC       Asp sequential transfer of a phosphate group between first an His and
CC       an Asp of the HK protein, followed by the transfer to a conserved His
CC       of the HPt protein and finally the transfer to an Asp in the receiver
CC       domain of the RR protein. {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Dwarf, narrow leaf, low tillering, abnormal hull,
CC       viviparous and low fertility phenotype. {ECO:0000269|PubMed:16891544}.
CC   -!- SIMILARITY: Belongs to the ARR family. Type-A subfamily. {ECO:0000305}.
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DR   EMBL; BR000313; FAA00265.1; -; Genomic_DNA.
DR   EMBL; AB249655; BAE79349.1; -; mRNA.
DR   EMBL; AP004043; BAD22948.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF10527.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS81741.1; -; Genomic_DNA.
DR   EMBL; CM000139; EAZ25187.1; -; Genomic_DNA.
DR   RefSeq; XP_015625250.1; XM_015769764.1.
DR   RefSeq; XP_015625251.1; XM_015769765.1.
DR   RefSeq; XP_015625252.1; XM_015769766.1.
DR   RefSeq; XP_015625253.1; XM_015769767.1.
DR   AlphaFoldDB; Q6K9T0; -.
DR   SMR; Q6K9T0; -.
DR   STRING; 4530.OS02T0830200-01; -.
DR   PaxDb; Q6K9T0; -.
DR   PRIDE; Q6K9T0; -.
DR   EnsemblPlants; Os02t0830200-01; Os02t0830200-01; Os02g0830200.
DR   GeneID; 4331245; -.
DR   Gramene; Os02t0830200-01; Os02t0830200-01; Os02g0830200.
DR   KEGG; osa:4331245; -.
DR   eggNOG; KOG1601; Eukaryota.
DR   HOGENOM; CLU_000445_69_5_1; -.
DR   InParanoid; Q6K9T0; -.
DR   OMA; ANFYLVK; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6K9T0; OS.
DR   GO; GO:0005829; C:cytosol; IDA:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR045279; ARR-like.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43874; PTHR43874; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   2: Evidence at transcript level;
KW   Cytokinin signaling pathway; Cytoplasm; Nucleus; Phosphoprotein;
KW   Reference proteome; Transcription; Transcription regulation;
KW   Two-component regulatory system.
FT   CHAIN           1..131
FT                   /note="Two-component response regulator ORR3"
FT                   /id="PRO_0000433820"
FT   DOMAIN          12..129
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   MOD_RES         62
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   131 AA;  14900 MW;  EBE61A1A441C6438 CRC64;
     MSTKTVPEPE PHVLAVDDSI VDRTVISRLL RSSKYRVTTV DSGKRALEVL SLDRNVHMII
     TDYCMPEMTG FDLLKRVKES AELKEIPVVL MSSENSPTRI RRCLEEGAED FLIKPVRPSD
     VSRLCNRVIM K