ID   ORR8_ORYSJ              Reviewed;         121 AA.
AC   Q8GVV6; A0A0P0XFF3;
DT   16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Two-component response regulator ORR8 {ECO:0000305};
DE   AltName: Full=OsRR8 {ECO:0000303|PubMed:16919402};
DE   AltName: Full=OsRRA13 {ECO:0000303|PubMed:16891544};
GN   Name=RR8 {ECO:0000303|PubMed:17284581};
GN   OrderedLocusNames=Os08g0376700 {ECO:0000312|EMBL:AP008214},
GN   LOC_Os08g28900 {ECO:0000305};
GN   ORFNames=OJ1705_C03.116 {ECO:0000312|EMBL:BAC45098.1},
GN   P0436B06.42 {ECO:0000312|EMBL:BAD05296.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16919402; DOI=10.1016/j.gene.2006.06.020;
RA   Ito Y., Kurata N.;
RT   "Identification and characterization of cytokinin-signalling gene families
RT   in rice.";
RL   Gene 382:57-65(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=17293362; DOI=10.1093/pcp/pcm022;
RA   Hirose N., Makita N., Kojima M., Kamada-Nobusada T., Sakakibara H.;
RT   "Overexpression of a type-A response regulator alters rice morphology and
RT   cytokinin metabolism.";
RL   Plant Cell Physiol. 48:523-539(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=16891544; DOI=10.1104/pp.106.086371;
RA   Pareek A., Singh A., Kumar M., Kushwaha H.R., Lynn A.M.,
RA   Singla-Pareek S.L.;
RT   "Whole-genome analysis of Oryza sativa reveals similar architecture of two-
RT   component signaling machinery with Arabidopsis.";
RL   Plant Physiol. 142:380-397(2006).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=17284581; DOI=10.1104/pp.106.093666;
RA   Schaller G.E., Doi K., Hwang I., Kieber J.J., Khurana J.P., Kurata N.,
RA   Mizuno T., Pareek A., Shiu S.H., Wu P., Yip W.K.;
RT   "Nomenclature for two-component signaling elements of rice.";
RL   Plant Physiol. 143:555-557(2007).
CC   -!- FUNCTION: Functions as response regulator involved in His-to-Asp
CC       phosphorelay signal transduction system. Phosphorylation of the Asp
CC       residue in the receiver domain activates the ability of the protein to
CC       promote the transcription of target genes. Type-A response regulators
CC       seem to act as negative regulators of the cytokinin signaling.
CC       {ECO:0000250|UniProtKB:Q9ZWS9}.
CC   -!- TISSUE SPECIFICITY: Expressed in flowers and panicles.
CC       {ECO:0000269|PubMed:16919402}.
CC   -!- PTM: Two-component system major event consists of a His-to-Asp
CC       phosphorelay between a sensor histidine kinase (HK) and a response
CC       regulator (RR). In plants, the His-to-Asp phosphorelay involves an
CC       additional intermediate named Histidine-containing phosphotransfer
CC       protein (HPt). This multistep phosphorelay consists of a His-Asp-His-
CC       Asp sequential transfer of a phosphate group between first an His and
CC       an Asp of the HK protein, followed by the transfer to a conserved His
CC       of the HPt protein and finally the transfer to an Asp in the receiver
CC       domain of the RR protein. {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Dwarf, narrow leaves, low tillering and low
CC       fertility phenotypes. {ECO:0000269|PubMed:16891544}.
CC   -!- SIMILARITY: Belongs to the ARR family. Type-A subfamily. {ECO:0000305}.
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DR   EMBL; BR000317; FAA00269.1; -; Genomic_DNA.
DR   EMBL; AB249663; BAE79357.1; -; mRNA.
DR   EMBL; AP003962; BAC45098.1; -; Genomic_DNA.
DR   EMBL; AP004397; BAD05296.1; -; Genomic_DNA.
DR   EMBL; AP008214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP014964; BAT05199.1; -; Genomic_DNA.
DR   RefSeq; XP_015649695.1; XM_015794209.1.
DR   AlphaFoldDB; Q8GVV6; -.
DR   SMR; Q8GVV6; -.
DR   STRING; 4530.OS08T0376700-01; -.
DR   PaxDb; Q8GVV6; -.
DR   PRIDE; Q8GVV6; -.
DR   EnsemblPlants; Os08t0376700-01; Os08t0376700-01; Os08g0376700.
DR   GeneID; 107275387; -.
DR   Gramene; Os08t0376700-01; Os08t0376700-01; Os08g0376700.
DR   KEGG; osa:107275387; -.
DR   eggNOG; KOG1601; Eukaryota.
DR   HOGENOM; CLU_000445_69_5_1; -.
DR   InParanoid; Q8GVV6; -.
DR   OMA; AWGIINT; -.
DR   OrthoDB; 1491046at2759; -.
DR   Proteomes; UP000000763; Chromosome 8.
DR   Proteomes; UP000059680; Chromosome 8.
DR   Genevisible; Q8GVV6; OS.
DR   GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR045279; ARR-like.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43874; PTHR43874; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   2: Evidence at transcript level;
KW   Cytokinin signaling pathway; Phosphoprotein; Reference proteome;
KW   Transcription; Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..121
FT                   /note="Two-component response regulator ORR8"
FT                   /id="PRO_0000433830"
FT   DOMAIN          5..121
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   MOD_RES         55
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   121 AA;  13675 MW;  36D0A7F68C4C7A1E CRC64;
     MSSPHVLVVD DTHVDRHVVS MALMRHNVRV TAVESVMQAL MFLDSEHDVD MIVSDYCMPD
     MTGYNLLMEV KKSPKLAHLP VVIASSDNIP ERIRKCLDGG AKDYILKPVK IVDVPRIMKY
     I