ID   ORUR_PSEAE              Reviewed;         339 AA.
AC   P72171;
DT   19-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Ornithine utilization regulator;
GN   Name=oruR; OrderedLocusNames=PA0831;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=9401045; DOI=10.1128/jb.179.24.7834-7842.1997;
RA   Hebert M.D., Houghton J.E.;
RT   "Regulation of ornithine utilization in Pseudomonas aeruginosa (PAO1) is
RT   mediated by a transcriptional regulator, OruR.";
RL   J. Bacteriol. 179:7834-7842(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Probably activates the ArgJ gene that encodes ornithine
CC       acetyltransferase. Binds to its own promoter-operator region. Probably
CC       binds ornithine.
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DR   EMBL; U73506; AAB94774.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG04220.1; -; Genomic_DNA.
DR   PIR; G83540; G83540.
DR   RefSeq; NP_249522.1; NC_002516.2.
DR   RefSeq; WP_003114220.1; NZ_QZGE01000007.1.
DR   AlphaFoldDB; P72171; -.
DR   SMR; P72171; -.
DR   STRING; 287.DR97_1113; -.
DR   PaxDb; P72171; -.
DR   EnsemblBacteria; AAG04220; AAG04220; PA0831.
DR   GeneID; 878384; -.
DR   KEGG; pae:PA0831; -.
DR   PATRIC; fig|208964.12.peg.862; -.
DR   PseudoCAP; PA0831; -.
DR   HOGENOM; CLU_047522_3_1_6; -.
DR   InParanoid; P72171; -.
DR   OMA; ANFSHAF; -.
DR   PhylomeDB; P72171; -.
DR   BioCyc; PAER208964:G1FZ6-845-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006593; P:ornithine catabolic process; IMP:PseudoCAP.
DR   InterPro; IPR032687; AraC-type_N.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF12625; Arabinose_bd; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..339
FT                   /note="Ornithine utilization regulator"
FT                   /id="PRO_0000194543"
FT   DOMAIN          241..338
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        258..279
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        305..328
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   339 AA;  37610 MW;  F1376ED624E97270 CRC64;
     MKQPLNFTAE LVPVAYAEAL LDLVAEYGVS RQALFDAARV RPEVLDSPNG RLSFLDFNQL
     TYSAQALCGE PALGLVLGQR LNVSAHGILG YAVLSSANLG KAIQFALKYY RVLGLAYELE
     LVLDDGRAEL RAVESMPLGA ASVFAAEGLM ATLYSIACFL VGEPLQDVRV GFAYPPPAHA
     RRYAEVFGVA AEFEQPWHWL SMPSEYLERP MALANPATVQ MCEQQCEALL ATLDVQEGLL
     TRVRRLLLAR PGDFPDLEQA ARELHTSGRS LRRHLSSLGT TYQQVLDDVR KRLALQYLTT
     TQLPLYEIAL LLGFNDSSNF RRAFRKWTGK LPSDYREAP