ID   OSA_SHIFL               Reviewed;         189 AA.
AC   P29772;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Protein osa;
GN   Name=osa;
OS   Shigella flexneri.
OG   Plasmid IncW pSa.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1832152; DOI=10.1128/jb.173.17.5449-5456.1991;
RA   Close S.M., Kado C.I.;
RT   "The osa gene of pSa encodes a 21.1-kilodalton protein that suppresses
RT   Agrobacterium tumefaciens oncogenicity.";
RL   J. Bacteriol. 173:5449-5456(1991).
RN   [2]
RP   INVOLVEMENT IN SUPPRESSION OF ONCOGENICITY.
RX   PubMed=8083162; DOI=10.1128/jb.176.18.5697-5703.1994;
RA   Chen C.Y., Kado C.I.;
RT   "Inhibition of Agrobacterium tumefaciens oncogenicity by the osa gene of
RT   pSa.";
RL   J. Bacteriol. 176:5697-5703(1994).
CC   -!- FUNCTION: Suppression of A.tumefaciens oncogenicity.
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DR   EMBL; U30471; AAA75248.1; -; Genomic_DNA.
DR   PIR; S23149; S23149.
DR   PDB; 4O7K; X-ray; 1.75 A; A=3-189.
DR   PDB; 4OVB; X-ray; 2.03 A; A=3-189.
DR   PDBsum; 4O7K; -.
DR   PDBsum; 4OVB; -.
DR   AlphaFoldDB; P29772; -.
DR   SMR; P29772; -.
DR   CDD; cd16389; FIN; 1.
DR   InterPro; IPR035615; FiwA/Osa.
PE   1: Evidence at protein level;
KW   3D-structure; Plasmid.
FT   CHAIN           1..189
FT                   /note="Protein osa"
FT                   /id="PRO_0000058085"
FT   HELIX           4..24
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   TURN            25..27
FT                   /evidence="ECO:0007829|PDB:4OVB"
FT   STRAND          34..36
FT                   /evidence="ECO:0007829|PDB:4OVB"
FT   STRAND          39..42
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          44..47
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          55..58
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          67..72
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   HELIX           73..81
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          85..87
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   HELIX           94..99
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   HELIX           103..112
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          122..128
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          131..138
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   HELIX           140..148
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          152..160
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   HELIX           161..171
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   STRAND          172..174
FT                   /evidence="ECO:0007829|PDB:4O7K"
FT   HELIX           179..189
FT                   /evidence="ECO:0007829|PDB:4O7K"
SQ   SEQUENCE   189 AA;  21080 MW;  FDFD0239CED38142 CRC64;
     MLMLLRRRCR AWLEIRRLDK ELAQSSGLPL ELPQIVPNAW NEVVWRLPVP NHPDAFMTAS
     NAAQSDFIVY VNGLAFYRAW LALGVEDSQA CPLKQDMPKD RKYPSSAAHF AVGIDSPVPL
     ADVSPTMILG HFAVCFTDGM TRSMWLLAHE VAVFPVLSRD EASAVMLAEH VGVAAPIQVS
     KLREQCRKI