ID   OSB10_DICDI             Reviewed;         390 AA.
AC   Q54NM4;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Oxysterol-binding protein 10;
DE   AltName: Full=OSBPj;
GN   Name=osbJ; ORFNames=DDB_G0285141;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the OSBP family. {ECO:0000305}.
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DR   EMBL; AAFI02000074; EAL64883.1; -; Genomic_DNA.
DR   RefSeq; XP_639892.1; XM_634800.1.
DR   AlphaFoldDB; Q54NM4; -.
DR   SMR; Q54NM4; -.
DR   PaxDb; Q54NM4; -.
DR   PRIDE; Q54NM4; -.
DR   EnsemblProtists; EAL64883; EAL64883; DDB_G0285141.
DR   GeneID; 8624963; -.
DR   KEGG; ddi:DDB_G0285141; -.
DR   dictyBase; DDB_G0285141; osbJ.
DR   eggNOG; KOG2210; Eukaryota.
DR   HOGENOM; CLU_012334_1_0_1; -.
DR   InParanoid; Q54NM4; -.
DR   OMA; WEPLFFK; -.
DR   PhylomeDB; Q54NM4; -.
DR   Reactome; R-DDI-1482801; Acyl chain remodelling of PS.
DR   Reactome; R-DDI-192105; Synthesis of bile acids and bile salts.
DR   Reactome; R-DDI-9013407; RHOH GTPase cycle.
DR   PRO; PR:Q54NM4; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0032934; F:sterol binding; IBA:GO_Central.
DR   GO; GO:0015248; F:sterol transporter activity; IBA:GO_Central.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   PANTHER; PTHR10972; PTHR10972; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   SUPFAM; SSF144000; SSF144000; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..390
FT                   /note="Oxysterol-binding protein 10"
FT                   /id="PRO_0000328473"
SQ   SEQUENCE   390 AA;  44462 MW;  1C14B581C8F4AEF0 CRC64;
     MTDISDESNI GYEEEVEEEI MEDDLDINND GCDGEDKKKN SGFLKQFASK QPFYKMSLPI
     SYSEPRSFLE KLSDQGSFLD ILLKVKNIEN EDDRFLEILK FYLSGWIQQK IAKSPFNPVI
     GETYQCKWVH KDGSTTEYIA EQISHHPPSS SFCMHNQQNG VIFHSHLSPT SKFWGNSLEN
     SMEGKLVYEI PSLQEEYIVE APKIIVKGVL VGSLSTETVG STNLTCKKTG YSAEIEFKGK
     GLFKSKHSLL VKVKHPSSKK ALYTLEGKFD GTVSITSTKT GKTTAFFDIN SDQIQPITSP
     LHELEENNSR VVWKHVIENL LNNNEDEASK QKTIVEENQR NLAKTREGKP WIPKNFIKVD
     NDDNEDSANQ NNVYYYSKLI EIRKEIMKNN