ID   OSB7_DICDI              Reviewed;         422 AA.
AC   Q54RM1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Oxysterol-binding protein 7;
DE   AltName: Full=OSBPg;
GN   Name=osbG; ORFNames=DDB_G0283035;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the OSBP family. {ECO:0000305}.
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DR   EMBL; AAFI02000049; EAL65961.1; -; Genomic_DNA.
DR   RefSeq; XP_639330.1; XM_634238.1.
DR   AlphaFoldDB; Q54RM1; -.
DR   SMR; Q54RM1; -.
DR   PaxDb; Q54RM1; -.
DR   EnsemblProtists; EAL65961; EAL65961; DDB_G0283035.
DR   GeneID; 8623901; -.
DR   KEGG; ddi:DDB_G0283035; -.
DR   dictyBase; DDB_G0283035; osbG.
DR   eggNOG; KOG2210; Eukaryota.
DR   HOGENOM; CLU_651223_0_0_1; -.
DR   InParanoid; Q54RM1; -.
DR   OMA; FSAKFHM; -.
DR   PhylomeDB; Q54RM1; -.
DR   Reactome; R-DDI-1482801; Acyl chain remodelling of PS.
DR   PRO; PR:Q54RM1; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0032934; F:sterol binding; IBA:GO_Central.
DR   GO; GO:0015248; F:sterol transporter activity; IBA:GO_Central.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   PANTHER; PTHR10972; PTHR10972; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   SUPFAM; SSF144000; SSF144000; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..422
FT                   /note="Oxysterol-binding protein 7"
FT                   /id="PRO_0000328477"
FT   REGION          283..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          402..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          354..384
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   422 AA;  47374 MW;  8ECB5AAB1212449B CRC64;
     MEADPSLVSY ADQHGEWETR EISIFGVVKS FISQLSIGQE LTKVSMPSIF LMPYSILELA
     ASRHLKYIHL LISAQHEEDP LKRMAIIIQY FFSCVRDGNF QKKPYNALLG EVHKCFVKYP
     SYDGQSTSTA QFIGEQVTHH PPLTAFNITT SEGITLDCNV QFSAKFHMNS VSVVTTGAVK
     ICIPVKVGNQ IIKETYIIDK GLPDALVKNV IFGTRSIYWT DSVDIMCEDS KTSATVHFDK
     NEYVKGEVSV YNTELEVEEH RASLKGYISD VVNIDYLESK SSEAAPASSA SKKEKKKEKK
     KAKHSKHTCS PSDTILMDTK QLEPNSTLYP KQTDPITSLG TWKEVTKQIV AGDMQAADQI
     KKEIEDEQRK RLQITKEEEK KERAYFKYND DKEIWEFKST QTLAPVSNST SSTASDAASG
     SN