ID   OSBL9_PONAB             Reviewed;         736 AA.
AC   Q5R9W4;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Oxysterol-binding protein-related protein 9;
DE            Short=ORP-9;
DE            Short=OSBP-related protein 9;
GN   Name=OSBPL9;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Heterodimer with OSBPL11. Interacts with OSBPL10.
CC       {ECO:0000250|UniProtKB:Q96SU4}.
CC   -!- SUBCELLULAR LOCATION: Late endosome membrane {ECO:0000250}. Golgi
CC       apparatus, trans-Golgi network membrane {ECO:0000250}. Note=Localizes
CC       at the Golgi-late endosome interface. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OSBP family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR859267; CAH91446.1; -; mRNA.
DR   RefSeq; NP_001125850.1; NM_001132378.1.
DR   AlphaFoldDB; Q5R9W4; -.
DR   SMR; Q5R9W4; -.
DR   STRING; 9601.ENSPPYP00000001579; -.
DR   PRIDE; Q5R9W4; -.
DR   GeneID; 100172780; -.
DR   KEGG; pon:100172780; -.
DR   CTD; 114883; -.
DR   eggNOG; KOG2210; Eukaryota.
DR   InParanoid; Q5R9W4; -.
DR   OrthoDB; 949920at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   InterPro; IPR018494; Oxysterol-bd_CS.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR10972; PTHR10972; 2.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF144000; SSF144000; 1.
DR   PROSITE; PS01013; OSBP; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Endosome; Golgi apparatus; Lipid transport; Lipid-binding;
KW   Membrane; Phosphoprotein; Reference proteome; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
FT   CHAIN           2..736
FT                   /note="Oxysterol-binding protein-related protein 9"
FT                   /id="PRO_0000366290"
FT   DOMAIN          2..99
FT                   /note="PH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT   REGION          231..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        250..289
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..351
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..368
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
FT   MOD_RES         306
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
FT   MOD_RES         324
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
FT   MOD_RES         325
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
FT   MOD_RES         326
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
FT   MOD_RES         329
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
FT   MOD_RES         611
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96SU4"
SQ   SEQUENCE   736 AA;  83207 MW;  B320319B34DD02DE CRC64;
     MASIMEGPLC KWTNVMKGWQ YRWFVLDYNA GLLSYYTSND KMMRGSRRGC VRLRGAVIGI
     DDEDDSTFTI TVDQKTFHFQ ARDADEREKW IHALEETILR HTLQLQGLDS GFVPSVQDFD
     KKLTEADAYL QILIEQLKLF DDKLQNCKED EQRKKIETLK ETTNSMVESI KHCIVLLQIA
     KDQSNAEKHA DGMISTINPV DAIYQPSPLE PVISTMPSQT VLPPEPVQLC KSEQRPSSLP
     VGPVLATLGH HQTPTPNSTG SGHSPPTSSL TSPSHVNLSP NTVPEFSYSS SEDEFYDADE
     FHQSGSSPKR LIDSSGSASV LTHSSSGNSL KRPDTTESLN SSMSNGTSGA DLFDSHDDRD
     DDAEAGSVEE HKSVIMHLLS QVRLGMDLTK VVLPTFILER RSLLEMYADF FAHPDLFVSI
     SDQKDPKDRM VQVVKWYLSA FHAGRKGSVA KKPYNPILGE IFQCYWTLPN DTEENTELVS
     EGPVPWVSKN SVTFVAEQVS HHPPISAFYA ECFNKKIQFN AHIWTKSKFL GMSIGVHNIG
     QGCVSCLDYD EHYILTFPNG YGRSIFTVPW VELGGECNIN CSKTGYSANI IFHTKPFYGG
     KKHRITAEIF SPNDKKSFCS VEGEWNGVMY AKYATGENTV FVDTKKLPII KKKVRKLEDQ
     NEYESRSLWK DVTFNLKIRD IDAATEAKHR LEERQRAEAR ERKEKEIQWE TRLFHEDGEC
     WVYDEPLLKR LGAAKH