ID   OSCP1_RAT               Reviewed;         379 AA.
AC   Q4QQS3;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Protein OSCP1;
GN   Name=Oscp1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   TISSUE SPECIFICITY.
RX   PubMed=16006562; DOI=10.1074/jbc.m504246200;
RA   Kobayashi Y., Shibusawa A., Saito H., Ohshiro N., Ohbayashi M., Kohyama N.,
RA   Yamamoto T.;
RT   "Isolation and functional characterization of a novel organic solute
RT   carrier protein, hOSCP1.";
RL   J. Biol. Chem. 280:32332-32339(2005).
CC   -!- FUNCTION: May be involved in drug clearance in the placenta.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Basal cell membrane {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Predominantly expressed in testis.
CC       {ECO:0000269|PubMed:16006562}.
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DR   EMBL; BC098048; AAH98048.1; -; mRNA.
DR   RefSeq; NP_001025094.1; NM_001029923.1.
DR   AlphaFoldDB; Q4QQS3; -.
DR   BioGRID; 263565; 2.
DR   STRING; 10116.ENSRNOP00000034112; -.
DR   PaxDb; Q4QQS3; -.
DR   Ensembl; ENSRNOT00000037246; ENSRNOP00000034112; ENSRNOG00000026978.
DR   GeneID; 362595; -.
DR   KEGG; rno:362595; -.
DR   UCSC; RGD:1306596; rat.
DR   CTD; 127700; -.
DR   RGD; 1306596; Oscp1.
DR   eggNOG; KOG4033; Eukaryota.
DR   GeneTree; ENSGT00390000004808; -.
DR   HOGENOM; CLU_039360_1_0_1; -.
DR   InParanoid; Q4QQS3; -.
DR   OMA; MMVKYQL; -.
DR   OrthoDB; 1398008at2759; -.
DR   PRO; PR:Q4QQS3; -.
DR   Proteomes; UP000002494; Chromosome 5.
DR   Bgee; ENSRNOG00000026978; Expressed in testis and 19 other tissues.
DR   Genevisible; Q4QQS3; RN.
DR   GO; GO:0009925; C:basal plasma membrane; ISO:RGD.
DR   GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; ISO:RGD.
DR   GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; ISO:RGD.
DR   InterPro; IPR019332; OSCP1.
DR   PANTHER; PTHR21439; PTHR21439; 1.
DR   Pfam; PF10188; Oscp1; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transport.
FT   CHAIN           1..379
FT                   /note="Protein OSCP1"
FT                   /id="PRO_0000251967"
SQ   SEQUENCE   379 AA;  43313 MW;  41B0FE8FBD8D31B2 CRC64;
     MSVRTLPLLF LNLGGEMLYV LDQRLRAQNI PGDKARKVLN DIISTMFNRK FTEELFKPQE
     LYSKKALRTV YDRLAHASIM RLNQASMDKL YDLMTMAFKY QVLLCPRPKD VLLVTFNHLD
     SIKGFIQDSP TIIHQVDETF RQLTEIYGSL SAGEFQLIRQ TLLIFFQDLH IRVSTFLKDK
     VQNSNGRFVL PVSGPVPWGI EVPGVIRVFN DKGDEVKRME FRHGGDYVAA HKEGSFELYG
     DRVLKLGTNM YSASRPVETH MSATSKNSAS RAQENIAPNP LAKEELNFLA RLIGGMEIKK
     PSGPEPGFRL NLFTTDEEEE HAALSRPEEL SYEVISIQAT QDQQRSEELA RIMEEFEMTE
     QPERNTSKGD DLLAMMDRL