OSC_DROME
ID OSC_DROME Reviewed; 135 AA.
AC Q23971; C9QNY5; Q9VHX8;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 3.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Antennal-specific protein OS-C;
DE Flags: Precursor;
GN Name=Os-C; ORFNames=CG3250;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Carlson J., Booth B., Frise E., Sandler J., Wan K., Yu C., Celniker S.;
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 15-135.
RC STRAIN=CS-5; TISSUE=Antenna;
RX PubMed=8206941; DOI=10.1016/s0021-9258(17)34013-9;
RA McKenna M.P., Hekmat-Scafe D.S., Gaines P., Carlson J.R.;
RT "Putative Drosophila pheromone-binding proteins expressed in a subregion of
RT the olfactory system.";
RL J. Biol. Chem. 269:16340-16347(1994).
CC -!- TISSUE SPECIFICITY: Antenna. In the third antennal segment. Expressed
CC in sencilla coeloconica.
CC -!- DEVELOPMENTAL STAGE: Expressed in adult but not in larval olfactory
CC organs.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA21357.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=ACX30029.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE014297; AAF54171.3; -; Genomic_DNA.
DR EMBL; BT099867; ACX30029.1; ALT_INIT; mRNA.
DR EMBL; U02545; AAA21357.1; ALT_INIT; mRNA.
DR RefSeq; NP_649753.3; NM_141496.3.
DR AlphaFoldDB; Q23971; -.
DR SMR; Q23971; -.
DR BioGRID; 66127; 2.
DR DIP; DIP-18679N; -.
DR IntAct; Q23971; 2.
DR DNASU; 40942; -.
DR EnsemblMetazoa; FBtr0300321; FBpp0289549; FBgn0010401.
DR GeneID; 40942; -.
DR KEGG; dme:Dmel_CG3250; -.
DR UCSC; CG3250-RB; d. melanogaster.
DR CTD; 40942; -.
DR FlyBase; FBgn0010401; Os-C.
DR VEuPathDB; VectorBase:FBgn0010401; -.
DR InParanoid; Q23971; -.
DR PhylomeDB; Q23971; -.
DR BioGRID-ORCS; 40942; 0 hits in 1 CRISPR screen.
DR ChiTaRS; Os-C; fly.
DR GenomeRNAi; 40942; -.
DR PRO; PR:Q23971; -.
DR Proteomes; UP000000803; Chromosome 3R.
DR Bgee; FBgn0010401; Expressed in head capsule and 9 other tissues.
DR ExpressionAtlas; Q23971; baseline and differential.
DR Genevisible; Q23971; DM.
PE 2: Evidence at transcript level;
KW Reference proteome; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..135
FT /note="Antennal-specific protein OS-C"
FT /id="PRO_0000021952"
FT REGION 43..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..63
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 15..17
FT /note="LLV -> AEL (in Ref. 4; ACX30029)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 135 AA; 14917 MW; A9E2C959B157B9D8 CRC64;
MGFHMGRQLL LSGFLLVMLQ MVTQTQARPQ DVITVAGEET EVVIKREGDD DGDDDDSSSE
ETVEDSEESR RRRREVNTDN TPSARAVIPG EQVVPILLEA ILPSVDAAGD RFARSVQFLK
NLTPGSELFA VEKNE
