OSMB_ECOLI
ID OSMB_ECOLI Reviewed; 72 AA.
AC P0ADA7; P17873;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Osmotically-inducible lipoprotein B;
DE Flags: Precursor;
GN Name=osmB; OrderedLocusNames=b1283, JW1275;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2644204; DOI=10.1128/jb.171.1.511-520.1989;
RA Jung J.U., Gutierrez C., Villarejo M.R.;
RT "Sequence of an osmotically inducible lipoprotein gene.";
RL J. Bacteriol. 171:511-520(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Provides resistance to osmotic stress. May be important for
CC stationary-phase survival.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- INDUCTION: By elevated osmotic pressure in the growth medium.
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DR EMBL; M22859; AAA24256.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74365.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA14837.1; -; Genomic_DNA.
DR PIR; A32255; LPECOB.
DR RefSeq; NP_415799.1; NC_000913.3.
DR RefSeq; WP_000498253.1; NZ_STEB01000005.1.
DR AlphaFoldDB; P0ADA7; -.
DR BioGRID; 4260738; 183.
DR STRING; 511145.b1283; -.
DR jPOST; P0ADA7; -.
DR PaxDb; P0ADA7; -.
DR PRIDE; P0ADA7; -.
DR EnsemblBacteria; AAC74365; AAC74365; b1283.
DR EnsemblBacteria; BAA14837; BAA14837; BAA14837.
DR GeneID; 66674892; -.
DR GeneID; 945866; -.
DR KEGG; ecj:JW1275; -.
DR KEGG; eco:b1283; -.
DR PATRIC; fig|511145.12.peg.1335; -.
DR EchoBASE; EB0673; -.
DR eggNOG; ENOG5032SFP; Bacteria.
DR HOGENOM; CLU_158447_1_2_6; -.
DR InParanoid; P0ADA7; -.
DR OMA; GVIGHET; -.
DR BioCyc; EcoCyc:EG10679-MON; -.
DR PRO; PR:P0ADA7; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0036405; C:anchored component of cell outer membrane; IDA:EcoCyc.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006970; P:response to osmotic stress; IEP:EcoCyc.
DR InterPro; IPR008816; Gly_zipper_2TM_dom.
DR Pfam; PF05433; Rick_17kDa_Anti; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..23
FT CHAIN 24..72
FT /note="Osmotically-inducible lipoprotein B"
FT /id="PRO_0000018069"
FT LIPID 24
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 24
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 72 AA; 6948 MW; 3C41F7B8E15DEA65 CRC64;
MFVTSKKMTA AVLAITLAMS LSACSNWSKR DRNTAIGAGA GALGGAVLTD GSTLGTLGGA
AVGGVIGHQV GK