OSMB_SALTY
ID OSMB_SALTY Reviewed; 72 AA.
AC P37723;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 19-DEC-2001, sequence version 2.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Osmotically-inducible lipoprotein B;
DE Flags: Precursor;
GN Name=osmB; OrderedLocusNames=STM1705;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 53-72.
RC STRAIN=LT2;
RX PubMed=2436909; DOI=10.1111/j.1432-1033.1987.tb11171.x;
RA Theisen M., Kelln R.A., Neuhard J.;
RT "Cloning and characterization of the pyrF operon of Salmonella
RT typhimurium.";
RL Eur. J. Biochem. 164:613-619(1987).
RN [3]
RP IDENTIFICATION.
RX PubMed=7920643; DOI=10.1038/ng0694-205;
RA Robison K., Gilbert W., Church G.M.;
RT "Large scale bacterial gene discovery by similarity search.";
RL Nat. Genet. 7:205-214(1994).
CC -!- FUNCTION: Provides resistance to osmotic stress. May be important for
CC stationary-phase survival (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC -!- INDUCTION: By elevated osmotic pressure in the growth medium.
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DR EMBL; AE006468; AAL20623.1; -; Genomic_DNA.
DR EMBL; X05382; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_460664.1; NC_003197.2.
DR RefSeq; WP_000481166.1; NC_003197.2.
DR AlphaFoldDB; P37723; -.
DR STRING; 99287.STM1705; -.
DR PaxDb; P37723; -.
DR EnsemblBacteria; AAL20623; AAL20623; STM1705.
DR GeneID; 1253224; -.
DR KEGG; stm:STM1705; -.
DR PATRIC; fig|99287.12.peg.1800; -.
DR HOGENOM; CLU_158447_1_2_6; -.
DR OMA; AGCADMT; -.
DR BioCyc; SENT99287:STM1705-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008816; Gly_zipper_2TM_dom.
DR Pfam; PF05433; Rick_17kDa_Anti; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 24..72
FT /note="Osmotically-inducible lipoprotein B"
FT /id="PRO_0000018070"
FT LIPID 24
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 24
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 72 AA; 6936 MW; 979B46CE9149AE31 CRC64;
MFMTSKKMAA AVLAITVAMS LSACSNWSKR DRNTAIGAGA GALGGAVLTD GSTLGTLGGA
AVGGVIGHQV GK