OSMY_ECOLI
ID OSMY_ECOLI Reviewed; 201 AA.
AC P0AFH8; P27291; Q2M5U2;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Osmotically-inducible protein Y;
DE Flags: Precursor;
GN Name=osmY; OrderedLocusNames=b4376, JW4338;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 29-43.
RC STRAIN=K12;
RX PubMed=1317380; DOI=10.1128/jb.174.11.3637-3644.1992;
RA Yim H.H., Villarejo M.;
RT "osmY, a new hyperosmotically inducible gene, encodes a periplasmic protein
RT in Escherichia coli.";
RL J. Bacteriol. 174:3637-3644(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=7610040; DOI=10.1093/nar/23.12.2105;
RA Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.;
RT "Analysis of the Escherichia coli genome VI: DNA sequence of the region
RT from 92.8 through 100 minutes.";
RL Nucleic Acids Res. 23:2105-2119(1995).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-12.
RX PubMed=8253679; DOI=10.1128/jb.175.24.7910-7917.1993;
RA Lange R., Barth M., Hengge-Aronis R.;
RT "Complex transcriptional control of the sigma s-dependent stationary-phase-
RT induced and osmotically regulated osmY (csi-5) gene suggests novel roles
RT for Lrp, cyclic AMP (cAMP) receptor protein-cAMP complex, and integration
RT host factor in the stationary-phase response of Escherichia coli.";
RL J. Bacteriol. 175:7910-7917(1993).
RN [6]
RP PROTEIN SEQUENCE OF 29-40.
RC STRAIN=K12 / EMG2;
RX PubMed=9298646; DOI=10.1002/elps.1150180807;
RA Link A.J., Robison K., Church G.M.;
RT "Comparing the predicted and observed properties of proteins encoded in the
RT genome of Escherichia coli K-12.";
RL Electrophoresis 18:1259-1313(1997).
RN [7]
RP PROTEIN SEQUENCE OF 29-32.
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9600841; DOI=10.1006/jmbi.1998.1726;
RA Wilkins M.R., Gasteiger E., Tonella L., Ou K., Tyler M., Sanchez J.-C.,
RA Gooley A.A., Walsh B.J., Bairoch A., Appel R.D., Williams K.L.,
RA Hochstrasser D.F.;
RT "Protein identification with N and C-terminal sequence tags in proteome
RT projects.";
RL J. Mol. Biol. 278:599-608(1998).
CC -!- SUBCELLULAR LOCATION: Periplasm.
CC -!- INDUCTION: By elevated osmotic pressure in the growth medium.
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DR EMBL; M89635; AAA16621.1; -; Unassigned_DNA.
DR EMBL; U14003; AAA97272.1; -; Genomic_DNA.
DR EMBL; U00096; AAC77329.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE78364.1; -; Genomic_DNA.
DR EMBL; S67278; AAP14005.1; -; Genomic_DNA.
DR PIR; A41899; A41899.
DR RefSeq; NP_418793.1; NC_000913.3.
DR RefSeq; WP_001295748.1; NZ_STEB01000033.1.
DR AlphaFoldDB; P0AFH8; -.
DR SMR; P0AFH8; -.
DR BioGRID; 4262791; 171.
DR BioGRID; 853172; 1.
DR DIP; DIP-47968N; -.
DR IntAct; P0AFH8; 4.
DR STRING; 511145.b4376; -.
DR jPOST; P0AFH8; -.
DR PaxDb; P0AFH8; -.
DR PRIDE; P0AFH8; -.
DR EnsemblBacteria; AAC77329; AAC77329; b4376.
DR EnsemblBacteria; BAE78364; BAE78364; BAE78364.
DR GeneID; 66671737; -.
DR GeneID; 948895; -.
DR KEGG; ecj:JW4338; -.
DR KEGG; eco:b4376; -.
DR PATRIC; fig|1411691.4.peg.2312; -.
DR EchoBASE; EB1364; -.
DR eggNOG; COG2823; Bacteria.
DR HOGENOM; CLU_084193_0_0_6; -.
DR InParanoid; P0AFH8; -.
DR OMA; DISVKTH; -.
DR PhylomeDB; P0AFH8; -.
DR BioCyc; EcoCyc:EG11391-MON; -.
DR PRO; PR:P0AFH8; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
DR GO; GO:0061077; P:chaperone-mediated protein folding; IDA:EcoCyc.
DR GO; GO:0006972; P:hyperosmotic response; IEP:EcoCyc.
DR GO; GO:0006970; P:response to osmotic stress; IBA:GO_Central.
DR InterPro; IPR007055; BON_dom.
DR InterPro; IPR014004; Transpt-assoc_nodulatn_dom_bac.
DR Pfam; PF04972; BON; 2.
DR SMART; SM00749; BON; 2.
DR PROSITE; PS50914; BON; 2.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Periplasm; Reference proteome; Repeat; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000269|PubMed:1317380,
FT ECO:0000269|PubMed:9298646, ECO:0000269|PubMed:9600841"
FT CHAIN 29..201
FT /note="Osmotically-inducible protein Y"
FT /id="PRO_0000021953"
FT DOMAIN 55..123
FT /note="BON 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00229"
FT DOMAIN 134..201
FT /note="BON 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00229"
SQ SEQUENCE 201 AA; 21074 MW; BF74D4388D984B93 CRC64;
MTMTRLKISK TLLAVMLTSA VATGSAYAEN NAQTTNESAG QKVDSSMNKV GNFMDDSAIT
AKVKAALVDH DNIKSTDISV KTDQKVVTLS GFVESQAQAE EAVKVAKGVE GVTSVSDKLH
VRDAKEGSVK GYAGDTATTS EIKAKLLADD IVPSRHVKVE TTDGVVQLSG TVDSQAQSDR
AESIAKAVDG VKSVKNDLKT K
