OSP4A_HUMAN
ID OSP4A_HUMAN Reviewed; 184 AA.
AC A0A2R8YFL7;
DT 10-OCT-2018, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2018, sequence version 1.
DT 03-AUG-2022, entry version 16.
DE RecName: Full=Oocyte-secreted protein 4A {ECO:0000305};
DE Flags: Precursor;
GN Name=OOSP4A {ECO:0000312|HGNC:HGNC:53904};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PLAC1 family. {ECO:0000305}.
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DR EMBL; AP000790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R8YFL7; -.
DR SMR; A0A2R8YFL7; -.
DR GlyGen; A0A2R8YFL7; 1 site.
DR MassIVE; A0A2R8YFL7; -.
DR Ensembl; ENST00000643613.1; ENSP00000495234.1; ENSG00000285375.1.
DR Ensembl; ENST00000645590.1; ENSP00000494103.1; ENSG00000285010.1.
DR MANE-Select; ENST00000645590.2; ENSP00000494103.1; NM_001395277.1; NP_001382206.1.
DR GeneCards; OOSP4A; -.
DR HGNC; HGNC:53904; OOSP4A.
DR HPA; ENSG00000285010; Not detected.
DR neXtProt; NX_A0A2R8YFL7; -.
DR VEuPathDB; HostDB:ENSG00000285010; -.
DR GeneTree; ENSGT00960000193304; -.
DR OMA; ITCSESW; -.
DR Pharos; A0A2R8YFL7; Tdark.
DR PRO; PR:A0A2R8YFL7; -.
DR Proteomes; UP000005640; Chromosome 11.
DR Bgee; ENSG00000285010; Expressed in blood and 47 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR033218; Oosp1/3/4.
DR InterPro; IPR033222; PLAC1_fam.
DR PANTHER; PTHR14380; PTHR14380; 1.
DR PANTHER; PTHR14380:SF3; PTHR14380:SF3; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..184
FT /note="Oocyte-secreted protein 4A"
FT /evidence="ECO:0000255"
FT /id="PRO_5015284893"
FT CARBOHYD 128
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 184 AA; 21040 MW; 7D264AA567BF687A CRC64;
MKISCVLGKL LMLFELIHGL QDLSITCSES WLQVKLRRTP LLNDLQPLQN ELSLGIGCPV
NMVEVDFFGF LYLLTFCGIR VSEHGVGILI ESLIVYEPTN FDFNLHIPVS CYVQRRFPII
LVMRGRENDS RRECRRSVGQ HRSLSHELED LEIRPRVSYV NSVPLLSYLI VSLPKCKNKA
VHSG