ID   OSPA4_BORBG             Reviewed;         274 AA.
AC   Q04851;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Outer surface protein A;
DE   Flags: Precursor;
GN   Name=ospA;
OS   Borreliella burgdorferi (Lyme disease spirochete) (Borrelia burgdorferi).
OG   Plasmid lp54.
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=139;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ZQ1;
RX   PubMed=1356932; DOI=10.1128/iai.60.11.4856-4866.1992;
RA   Wallich R., Helmes C., Schaible U.E., Lobet Y., Moter S.E., Kramer M.D.,
RA   Simon M.M.;
RT   "Evaluation of genetic divergence among Borrelia burgdorferi isolates by
RT   use of OspA, fla, HSP60, and HSP70 gene probes.";
RL   Infect. Immun. 60:4856-4866(1992).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
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DR   EMBL; X66065; CAA46865.1; -; Genomic_DNA.
DR   PIR; B49209; B49209.
DR   AlphaFoldDB; Q04851; -.
DR   SMR; Q04851; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR001809; OM_lipoprot_Borrelia.
DR   InterPro; IPR023322; OM_lipoprot_dom_sf.
DR   Pfam; PF00820; Lipoprotein_1; 1.
DR   PRINTS; PR00968; OUTRSURFACE.
DR   SUPFAM; SSF51087; SSF51087; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           17..274
FT                   /note="Outer surface protein A"
FT                   /id="PRO_0000018077"
FT   LIPID           17
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           17
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   274 AA;  29703 MW;  3670D5C540EFD883 CRC64;
     MKKYLLGIGL ILALIACKQN VSSLDEKNSV SVDLPGGMKV LVSKEKDKDG KYSLEATVDK
     LELKGTSDKN NGSGTLEGEK TDKSKVKLTI AEDLSKTTFE IFKEDGKTLV SKKVTLKDKS
     STEEKFNEKG EISEKTIVRA NGTRLEYTDI KSDGSGKAKE VLKDFTLEGT LAADGKTTLK
     VTEGTVVLSK NILKSGEITV ALDDSDTTQA TKKTGKWDSK TSTLTISVNS QKTKNLVFTK
     EDTITVQKYD SAGTNLEGKA VEITTLKELK DALK