ID   OSPA5_BORBG             Reviewed;         273 AA.
AC   Q09089;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Outer surface protein A;
DE   Flags: Precursor;
GN   Name=ospA;
OS   Borreliella burgdorferi (Lyme disease spirochete) (Borrelia burgdorferi).
OG   Plasmid lp54.
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=139;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PBI;
RX   PubMed=8432821; DOI=10.1128/jcm.31.2.340-350.1993;
RA   Zumstein G., Fuchs R., Hofmann A., Preac-Mursic V., Soutschek E.,
RA   Wilske B.;
RT   "An OspA serotyping system for Borrelia burgdorferi based on reactivity
RT   with monoclonal antibodies and OspA sequence analysis.";
RL   J. Clin. Microbiol. 31:340-350(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DK6;
RA   Karami A.;
RL   Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
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DR   EMBL; S48323; AAB23810.1; -; Genomic_DNA.
DR   EMBL; X83622; CAA58601.1; -; Genomic_DNA.
DR   PIR; S51108; S51108.
DR   AlphaFoldDB; Q09089; -.
DR   SMR; Q09089; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR001809; OM_lipoprot_Borrelia.
DR   InterPro; IPR023322; OM_lipoprot_dom_sf.
DR   Pfam; PF00820; Lipoprotein_1; 1.
DR   PRINTS; PR00968; OUTRSURFACE.
DR   SUPFAM; SSF51087; SSF51087; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Plasmid; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           17..273
FT                   /note="Outer surface protein A"
FT                   /id="PRO_0000018078"
FT   LIPID           17
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           17
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   273 AA;  29640 MW;  2EAEE12169A5325B CRC64;
     MKKYLLGIGL ILALIACKQN VSSLDEKNSV SVDLPGEMKV LVSKEKDKDG KYSLMATVDK
     LELKGTSDKS NGSGTLEGEK SDKSKAKLTI SEDLSKTTFE IFKEDGKTLV SKKVNSKDKS
     SIEEKFNAKG ELSEKTILRA NGTRLEYTEI KSDGTGKAKE VLKDFALEGT LAADKTTLKV
     TEGTVVLSKH IPNSGEITVE LNDSNSTQAT KKTGKWDSNT STLTISVNSK KTKNIVFTKE
     DTITVQKYDS AGTNLEGNAV EIKTLDELKN ALK